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An integrated sensing chip for attomolar label-free detection of amplified nucleic acids
Summary: Loop-mediated isothermal amplification (LAMP) is a nucleic acid amplification technique and has been widely used for detection of pathogens in many organisms. Current LAMP-based sensors usually require the LAMP products to be labeled in order for them to be detected. Description: This new LAMP chip offers a new portable platform to detect...
Published: 7/2/2024
Category(s): Agriculture, Engineering & Physical Sciences, Sensors & Controls, Research Tools & Design Tools, Medical Devices, Veterinary Medicine, Life Sciences, Healthcare
C1-I haploid inducer
Summary: The C1-I haploid inducer is a maternal haploid inducer line, fixed for the allele C1-I. C1 is a transcription factor in the anthocyanin pathway. The allele C1-I suppresses the formation of anthocyanin even in the presence of R1-nj, a visual selectable marker commonly used in haploid selection. Thus C1-I haploid inducer allows to induce and...
Published: 8/16/2023
Category(s): Agriculture, Life Sciences
Short-Chain Fatty-Acids to Mitigate Antimicrobial Resistance in the Gut
­Summary: This technology is a method to prevent horizontal gene transfer in bacteria that results in antibiotic resistant and multidrug resistant bacteria in humans and livestock though the use of short chain fatty acids Description: Antibiotic resistant (AR) and multidrug resistant (MDR) bacteria are growing threats to both animal and human...
Published: 7/22/2022
Category(s): Life Sciences, Healthcare, Veterinary Medicine
Porcine Rotavirus B and C Monoclonal Antibodies
Summary: The antibodies are likely to be the first ones recognizing the VP6 proteins in the marketplace. Description: Using molecular cloning and recombinant protein techniques, our inventors have produced several monoclonal antibodies against Porcine Rotavirus B and C. After screening tests and evaluation, monoclonal antibodies 10B1 and 11H3 were...
Published: 2/16/2022
Category(s): Life Sciences, Healthcare, Veterinary Medicine, Medical Devices, Research Tools & Design Tools
Bone Healing Apparatus
Summary: ISURF #5069 improves the end results for fractured long bones by utilizing 3D printing technology to produce individualized and high-tolerance bone rods. They are manufactured with FDA approved matertials. This technology allows increased control and rotation of long bone movement as compared to traditional methods of treatment, and yields...
Published: 2/16/2022
Category(s): Life Sciences, Healthcare, Veterinary Medicine, Medical Devices
Virtual Reality as a Tool to Evaluate Chicken Behavior and Improve Animal Welfare
Summary: Large-scale production poultry farms are needed to respond to high demand for eggs and poultry. Because of public concern for hen welfare, it is expected that the majority of US poultry housing will switch to cage-free systems in the near future. Disease outbreaks, cannibalism and feed cost are major concerns in cage-free housing. It is now...
Published: 2/16/2022
Category(s): Life Sciences
A Novel Facultative Methylotroph, Methylocystis daltona SB2
Description: Methylocystis daltona SB2 (SB2) is a novel facultative methanotroph capable of utilizing methane and other multi-carbon substrates for growth has been identified. SB2 constitutively expresses methane monooxygenase, enabling bioremediation of cholorinated solvents, enhanced removal of methane from the atmosphere, and for controlling emission...
Published: 2/11/2022
Category(s): Energy, Cleantech & Environmental, Life Sciences
A Novel Way to Extract and Combine the Large Data of Protein Sequences and Structures to Improve Matching Scores
Summary: Researchers at Iowa State University have developed a new amino acid substitution matrix, SeqStruct, that takes into account both the sequence and structure data of the protein in the sequence matching procedure. This allows for better sequence matching scores across diverse proteins, especially for those proteins whose structures are similar...
Published: 2/11/2022
Category(s): Life Sciences, Software & Information Technology
Gene controlling spontaneous haploid genome doubling in maize
Summary: ISU researchers identified a maize chromosomal region and markers associated with the ability of haploid plants to spontaneously double their genome, and thus become DH/inbred lines. Genome doubling without particular treatment, greenhouse cultivation and transplanting can substantially reduce the costs of DH line production. The chromosomal...
Published: 6/17/2022
Category(s): Agriculture, Life Sciences
Anti-Alpha-Synuclein Monoclonal Antibodies for Diagnostics and Therapeutics
Summary: Iowa State University researchers have developed anti-alpha-synuclein antibodies that preferentially bind to aggregated alpha-synuclein. The antibodies can be used for an early screening test for alpha-synuclein associated diseases (such as Parkinsons' disease) with potential therapeutic uses to include the treatment of Parkinsons' disease...
Published: 2/11/2022
Category(s): Life Sciences, Healthcare
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