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The antibodies are likely to be the first ones recognizing the VP6 proteins in the marketplace.

Tangible Materials. Commercial Ready.

Using molecular cloning and recombinant protein techniques, our inventors have produced several monoclonal antibodies against Porcine Rotavirus B and C. After screening tests and evaluation, monoclonal antibodies 10B1 and 11H3 were selected for binding to Porcine Rotavirus B and Porcine Rotavirus C, respectively.  Both antibodies are specific for the VP6 protein in each target virus or its corresponding recombinant protein.  The antibodies are of IgG isotype which makes them attractive for commercialization.  Mab 11H3 can detect the target Porcine Rotavirus C viral protein in intestinal tissues by fluorescent antibody technique and immunohistochemical staining. Iimmunohistochemical staining for PoRV-B using Mab 10B1 has yet to be established but both antibodies have uses using a variety of assays.

• The antibodies might become the first ones available in the marketplace for the detection of Porcine Rotavirus B and C.

• While several commercial serological assays are available for RVA, commercial RVB and RVC antibody assays are unavailable.

There is a commercial opportunity for the use of the antibodies as research tools and, they could be used for diagnostic kits.

Tangible Material