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An integrated sensing chip for attomolar label-free detection of amplified nucleic acids
Summary:
Loop-mediated isothermal amplification (LAMP) is a nucleic acid amplification technique and has been widely used for detection of pathogens in many organisms. Current LAMP-based sensors usually require the LAMP products to be labeled in order for them to be detected.
Description:
This new LAMP chip offers a new portable platform to detect...
Published: 7/2/2024
Category(s): Agriculture, Engineering & Physical Sciences, Sensors & Controls, Research Tools & Design Tools, Medical Devices, Veterinary Medicine, Life Sciences, Healthcare
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Method for Computer Modeling of Partially Coated Structures
Summary:
Our contributors have proposed a simple and efficient projection-based approach to modeling partial coatings on a structure. This integrated projection-based, isogeometric analysis directly incorporates the existing CAD model and material definitions and eliminates time-consuming geometry manipulation and meshing steps that are necessary...
Published: 7/22/2022
Category(s): Software & Information Technology, Research Tools & Design Tools
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Resonant sweat analysis sensor with wireless reader
Summary:
The innovative use of resonant sensors coupled with microfluidic channels enables the ability to measure sweat rate and conductivity, allowing additional information to be gathered such as electrolyte loss. A wireless reader gives access to this information without the need for onboard power and through PPE (no line-of-sight required).
Description:...
Published: 2/11/2022
Category(s): Healthcare, Medical Devices, Sensors & Controls, Research Tools & Design Tools
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Porcine Rotavirus B and C Monoclonal Antibodies
Summary:
The antibodies are likely to be the first ones recognizing the VP6 proteins in the marketplace.
Description:
Using molecular cloning and recombinant protein techniques, our inventors have produced several monoclonal antibodies against Porcine Rotavirus B and C. After screening tests and evaluation, monoclonal antibodies 10B1 and 11H3 were...
Published: 2/16/2022
Category(s): Life Sciences, Healthcare, Veterinary Medicine, Medical Devices, Research Tools & Design Tools
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Zwitterionic ionic liquids as gas chromatography stationary phases
Summary:
ISU researchers have developed an improved stationary phase for performing gas chromatography on carboxylic acids, glycols and alcohols.
Description:
Gas chromatography is the most common method of separating and quantifying carboxylic acids, including free fatty acids, but due to properties such as polarity, involatility, and thermal...
Published: 6/17/2022
Category(s): Engineering & Physical Sciences, Imaging, Research Tools & Design Tools
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Machine for Computing Casual Inference from Time Series Data
Summary: Iowa State University researchers have developed a novel algorithm approach for computing causal interaction from time series data. The proposed approach will help determine which time series data will cause or influence which other time series data, given two or more-time series data.
Stage1.png Development Stage:
Description: The detection...
Published: 2/11/2022
Category(s): Healthcare, Life Sciences, Research Tools & Design Tools, Software & Information Technology
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Logarithmic Photo-Converter with Huge Dynamic Range
Summary: This device is capable of measuring optical light levels that may vary from the single photon level up to many orders of magnitude larger illuminations. In fact, the upper range can be almost, apart from practical spatial details, as large as one desires. This device is possible due to the fact that the SiPMs can be exposed to daylight at full...
Published: 2/11/2022
Category(s): Engineering & Physical Sciences, Healthcare, Imaging, Medical Devices, Research Tools & Design Tools
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Rapid Enrichment of Viable Bacteria using Magnetic Ionic Liquids for PCR Amplification and Culture-Based Diagnostics
Summary:
ISU researchers have developed new molecules with an accompanying method to preconcentrate bacteria for rapid detection for food safety testing.
Description:
The detection of viable bacteria in food, environmental, or clinical samples is limited by time-consuming enrichment procedures (e.g., overnight cultures) that are often mandatory...
Published: 6/17/2022
Category(s): Life Sciences, Materials, Research Tools & Design Tools
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Transparent soil made by gel beads
Summary:
This innovation appears to be the first description of using beads made with “natural” gelling materials to observe plant roots. The bead formulation is novel and optimized for plant growth.
Description:
ISU researchers reported their invention to be a transparent soil medium which can provide a heterogeneous environment with...
Published: 5/20/2024
Category(s): Agriculture, Life Sciences, Research Tools & Design Tools
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High-Throughput selective capture of biological cells by dielectrophoresis at a bipolar electrode array
Summary:
ISU researchers have developed a device that employs an array of > 1,400 wireless electrodes for the continuous high-throughput isolation of cells that often are expressed in small concentrations.
Description:
ISURF #04548 describes an array of > 1,400 wireless bipolar electrodes (BPEs) in dielectrophoresis (DEP) devices. This allows...
Published: 6/17/2022
Category(s): Engineering & Physical Sciences, Medical Devices, Research Tools & Design Tools
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