ISU
Home
ISURF/OIPTT
Home
ISURFtech
Home
Advanced
Search
RSS
Feeds
Insect toxin delivery mediated by a densovirus coat protein
Category(s):
For Information, Contact:
Dario Valenzuela
Senior Commercialization Manager, Life Sciences
515-294-4740
licensing@iastate.edu
Web Published:
1/31/2017
ISURF #
4563
Summary:
A Junonia coenia densovirus coat protein with potential to create fusion proteins expressed in transgenic crops to control the fall armyworm.

Development Stage:
Description:
The fall armyworm is a continuous resident of the Gulf States. Corn, sorghum, and other plants of the grass family are its preferred foods, but the fall armyworm also attacks alfalfa, bean, peanut, potato, sweet potato, turnip, spinach, tomato, cabbage, cucumber, cotton, tobacco, all grain crops, and clover. Each year the fall armyworm can be found as far north as Montana, Michigan, and New Hampshire. In the southeast it occurs annually on late corn.

In this disclosure, ISU researchers report a discovery that may be exploited to develop a technology to control the armyworm without using chemical insecticides. The finding is that the VP4 coat protein from the Junonia coenia Densovirus rapidly crosses the midgut epithelium of this insect. Thus, there is an opportunity to develop effective insecticidal VP4/toxin fusion proteins capable to kill the worm by ingestion of the toxic proteins produced endogenously in a biotech crop.

Advantage:
• Possible alternative to chemical insecticides
• Likely not to disrupt non-plant eating insects
• Potential for high specificity
Application:
Pest control in plant agriculture.

References:
Patent Information:
*To see the full version of the patent(s), follow the link below, then click on "Images" button.

Patent:
Patent(s) applied for


Direct Link: