4827

This disclosure isolated a novel porcine sapelovirus (PSV) from a swine spinal cord sample.

Porcine Sapelovirus (PSV) is an emerging cause of atyptical neurological disease in swine resulting commonly in a herd mortality of 1-3%, and occasionally up to 10% on affected farms. Currently there is no purified cell-adapted PSV virus isolate reported obtained in the United States, so pathogenesis studies, genetic characterization, serological assays, in vitro characterization, and vaccine development are not available due to the lack of a PSV isolate.

Our inventors developed a pure cell adapted PSV isolate from a United States Swine farm to address the deficiencies above. This is the first and only PSV isolate adapted on ST cell line and IPEC-1 cells lines to the best of their knowledge, and the first reported PSV cultured on cells in the United States. This PSV isolate successfully grown in culture could be used for research purposes, diagnostics, and vaccine development, thus numerous PSV research projects and commercial product development will become possible. 

• Tangible material

• Recent isolate

Research purposes, diagnostics, and vaccine development for PSV.