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Magnetic two-way valves for paper based microfluidics: pathway for multi-step assays
Category(s):
For Information, Contact:
Mark Juetten
Associate Commercialization Manager, Chemistry
515-294-4740
licensing@iastate.edu
Web Published:
11/10/2017
ISURF #
4675
Summary:
ISU researchers developed a paper-fluidic valve that can reversibly switch fluid delivery into multiple channels with controlled volume and/or frequency. In terms of electric circuit equivalence, this valve is akin to a transistor or an SPDT relay, hence enables programmable fluid delivery.

Development Stage:
Description:
Point-of-care diagnostics are an area of emerging interest for many health-care applications, particularly in-home or personalized care. Paper microfluidic lab-on-a-chip technologies have attracted a lot of attention in this area due to their low cost, with the assays often being disposable. Switching and gating mechanisms that are possible in many non-paper lab-on-a-chip technologies are not possible in the paper based analogues however, so new solutions have to be developed in order for functionality of these diagnostic tests to be similar to the more expensive tests. In paper microfluidics, the development of smart, reversible, and versatile switches is critical for the regulation of fluid flow across multiple channels.  Common limitations of current switches include long response times, limited switching capabilities, and irreversibility. A gating mechanism that is reversible, quick, and versatile is therefore interesting. To respond to this market need Iowa State University researchers have developed a paper-based microfluidic valve, capable of being switched between multiple channels in a reversible fashion.

Advantage:
• Reversible
• Cheap
• Fast acting
• Multichanneled
• Programmable
• Power-free

Application:
Microfluidics, sample preparation, purification, separation, diagnostics, ordering fluids schemes
Patent Information:
*To see the full version of the patent(s), follow the link below, then click on "Images" button.


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