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Novel Protein Synthases for the Production of Bi-Functional Fatty Acids
Category(s):
For Information, Contact:
Craig Forney
Commercialization Manager, Chemistry and Materials Sciences
515-294-4740
licensing@iastate.edu
Web Published:
4/29/2016
ISURF #
4083
Summary:
ISU researchers have developed biocatalysts that make bi-functionalized molecules (fatty acids) and a recombinant bacterial expression system.

Development Stage:
Description:
Fatty acids normally synthesized in biological systems have only one functional group, carboxylic acid, which is found at the alpha end of the molecule. Bi-functional fatty acids, where there is also a functional group at the omega end of the molecule, are desirable for industrial applications, but are produced by only a few natural systems and at levels that are too low for practical replacement of petroleum-based sources of monomers.  Approaches that enable larger scale production of bi-functional fatty acids will help drive the use of bio-based chemicals. The technology addresses the need for efficient production of bi-functionalized fatty acids that can be used as precursors for the bio-based production of polymers, surfactants, and various specialty chemicals and has the potential to serve as the basis of development of tailored enzymes that are designed to incorporate different functionalities into fatty acids to produce a range of bi-functionalized precursor molecules.

Advantage:
• Produces bi-functional fatty acids
• Replacement for petroleum-based sources of monomers
• Serves a precursor for a wide variety of specialty chemicals, polymers, and surfactants
• Very lucrative market

Application:
Bio-based chemicals, Specialty chemicals
Patent Information:
*To see the full version of the patent(s), follow the link below, then click on "Images" button.
Country Serial No. Patent No. Issued Date
United States 14/762,791 9,809,804* 11/7/2017

Patent:
Patent(s) applied for

Direct Link: