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miRNA396 as a Tool to Control Cyst Nematodes
Category(s):
For Information, Contact:
Dario Valenzuela
Senior Commercialization Manager, Life Sciences
515-294-4740
licensing@iastate.edu
Web Published:
12/8/2015
ISURF #
3900
Summary:
The innovation is a molecular target to develop plants with enhanced resistance to nematodes.

Development Stage:
Description:
ISU researchers have demonstrated that the miRNA396-GRF regulatory unit in the model plant Arabidopsis mediates parasitism by the sugar beet nematode. Furthermore, the data indicates that the miRNA396 represents a key regulator for the reprogramming of root cells representing a powerful molecular target for the animal. Since miRNA396 is highly conserved in plants, manipulation of its expression in  agronomic crops may also lead to enhanced resistance to nematodes.

Advantage:
• Molecular modification approach
• Potential utility in many crop species

Application:
Construction of transgenic or gene edited plants with enhanced resistance to nematodes

References:
Patent Information:
*To see the full version of the patent(s), follow the link below, then click on "Images" button.

Patent:
Patent(s) applied for

Direct Link: