4425

ISU researchers have identified, purified, and characterized a cell-culture derived, plaque-cloned isolate of porcine deltacoronavirus (“ISU isolate”) from a clinical case

The ISU isolate has been adapted for propagation in a swine cell line for easy manipulation in vitro and its full-length genome has been sequenced. The ISU isolate has been demonstrated to cause diarrheic disease in conventional growing pigs, suggesting that it retains its original pathogenicity. The ISU isolate can be used as antigen for various vaccine formula (e.g., live, killed, genetically modified) and antibody production (both monoclonal and polyclonal antibodies) as well as for antibody assays (e.g., indirect FA test, ELISA, SN, Western immunoblot). Other uses include; positive control for viral assays such as PCR assays, and virus isolation.

• Adapted to growth in culture

• Can be used as antigen for various vaccine formula and antibody production

• Can be used as a positive control for viral assays such as PCR assays, and virus isolation

Veterinary Diagnostics

Tangible Material