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Porcine Deltacoronavirus
Category(s):
For Information, Contact:
Dario Valenzuela
Senior Commercialization Manager, Life Sciences
515-294-4740
licensing@iastate.edu
Web Published:
12/8/2015
ISURF #
4425
Summary:
ISU researchers have identified, purified, and characterized a cell-culture derived, plaque-cloned isolate of porcine deltacoronavirus (“ISU isolate”) from a clinical case

Development Stage:
Description:
The ISU isolate has been adapted for propagation in a swine cell line for easy manipulation in vitro and its full-length genome has been sequenced. The ISU isolate has been demonstrated to cause diarrheic disease in conventional growing pigs, suggesting that it retains its original pathogenicity. The ISU isolate can be used as antigen for various vaccine formula (e.g., live, killed, genetically modified) and antibody production (both monoclonal and polyclonal antibodies) as well as for antibody assays (e.g., indirect FA test, ELISA, SN, Western immunoblot). Other uses include; positive control for viral assays such as PCR assays, and virus isolation.

Advantage:
• Adapted to growth in culture
• Can be used as antigen for various vaccine formula and antibody production
• Can be used as a positive control for viral assays such as PCR assays, and virus isolation

Application:
Veterinary Diagnostics

Patent Information:
*To see the full version of the patent(s), follow the link below, then click on "Images" button.

Intellectual Property:
Tangible Material

Direct Link: