ISU
Home
ISURF/OIPTT
Home
ISURFtech
Home
Advanced
Search
RSS
Feeds
An Improved Synthsis of Coumalic Acid and Malic Acid from a Common Intermediate
Category(s):
For Information, Contact:
Craig Forney
Commercialization Manager, Chemistry and Materials Sciences
515-294-4740
licensing@iastate.edu
Web Published:
12/8/2015
ISURF #
4029
Summary:
Iowa State University researchers have developed a new synthesis route for coumalic acid from malic acid which uses far less corrosive conditions.

Development Stage:
Description:
Polyethylene terephthalate (PET) is one of the most widely used polymers used today.  PET is formed through a polycondensation reaction of ethylene terephthalate, which is itself a product of a reaction between ethylene glycol and terephthalic acid.  While the common route to produce terephthalic acid is by the oxidation of para-xylene, it is possible to produce the terephthalic acid from biorenewable sources, in particular from derivatives of coumalic acid.

Iowa State University researchers have developed a new synthetic route for coumalic acid from malic acid.  This new method eliminates the use of fuming sulfuric acid as a reagent, and instead uses dichloroethane as a solvent for the malic acid and a weak acid as the reagent.  These much more moderate reaction conditions should make scale up for production of coumalic acid much more feasible.  In addition, other products such as fumaric acid may also be synthesized by adjusting the reaction conditions.

Advantage:
• Mild reaction conditions
• Readily scalable

Application:
Biorenewable chemical for many uses, including textiles, beverage containers, and thermoformed parts

References:
Patent Information:
*To see the full version of the patent(s), follow the link below, then click on "Images" button.
Country Serial No. Patent No. Issued Date
United States 14/892,298 9,617,236* 4/11/2017


Direct Link: