4423

ISU researchers have developed highly specific monoclonal antibodies against human PKC δ. One of the antibodies of this invention (10F11B) is far superior to a widely-used commercial antibody. The researchers have used the 10F11B antibody to measure the PKC δ protein in primary mouse astrocytes and in mouse striatum and hippocampal tissue by Western blot analysis. In addition, the same antibody has been used for immunochemistry applications including identification of PKC δ in cell layers of the cerebellum.   The 10F11B hybridoma is available for licensing on a non-exclusive basis.

• Highly specific monoclonal antibody

• Superior to current commercially available antibody

• Suitable for ELISA, immunochemistry, and Western blot analysis

Research, Diagnostic Development