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Iowa State University researchers have identified, purified, and characterized cell culture-derived isolates of Senecavirus. A. The full genome sequence of the new isolates revealed that the isolates are genetically distinct from previously known Senecavirus A viruses.

Genetic changes/mutations have made the virus virulent, thus accounting for the 2015 vesicular disease outbreak in show and commercial pigs which have been seen in a number of States in the Midwest including IA, SD, IL, IN, MO, MN. From the rapid spreading and frequent identification of the virus, researchers concluded that prevention and control measures will be needed and that the isolates have value as tangible property for biologics and diagnostics. The isolates have been propagated continuously in culture to high titer at ISU and the idiopathic vesicular disease was reproduced with one isolate (in collaboration with the USDA). Propagation of the virus to a high titer will aid in producing vaccines and diagnostic reagents.

• Distinct new viral strains

• Full genome sequence available

• High titer will aid in producing vaccines and diagnostic reagents

• Addresses a niche market

Therapeutic / Vaccine Development

Tangible Material