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Modification of the Nodulating, Nitrogen-Fixing Soybean Symbiont Bradyrhizobium japonicum to Increase Plant Disease Resistance
Category(s):
For Information, Contact:
Dario Valenzuela
Senior Commercialization Manager, Life Sciences
515-294-4740
licensing@iastate.edu
Web Published:
12/7/2015
ISURF #
4119
Development Stage:
Description:
B. japonicum has a symbiotic relationship with legumes. In addition to its nitrogen-fixation role, it produces a number of plant hormones that influence growth.  However, these hormones can have other effects on the plant. For example, gibberellin produced by B. japonicum has been found to suppress host plant disease resistance.
ISU researchers have developed a B. japonicum strain with the gibberellin synthesis operon deleted. It has been found to have to have a ten-fold decrease in the number of viable bacteria, but produces no discernible effect on nodulation, nitrogen fixation/reduction, or plant growth. The inventors have thus hypothesized that B. japonicum uses gibberellin to suppress plant host defenses, making it more susceptible to infection by microbial pathogens. They further postulate that deletion of the operon encoding gibberellin biosynthesis can be used to develop an inoculant that will result in a plant with enhanced disease resistance.

Advantage:
• Increased innate disease resistance
• Increased yields
• Reduction in pesticide use
• Applicable to other legumes
• Large market

Application:
Production of soybeans and other legumes

Patent Information:
*To see the full version of the patent(s), follow the link below, then click on "Images" button.
Country Serial No. Patent No. Issued Date
United States 14/712,430 9,743,673* 8/29/2017


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