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pH-Sensitive Methacrylic Copolymer Gels
Category(s):
For Information, Contact:
Dario Valenzuela
Senior Commercialization Manager, Life Sciences
515-294-4740
licensing@iastate.edu
Web Published:
5/22/2015
ISURF #
2954
Development Stage:
Synthesis routes have been defined and materials have been produced, and ISU is seeking partners interested in commercializing this technology.
Description:
Iowa State University and Ames Laboratory researchers have developed an invention which provides novel gel forming methacrylic blocking copolymers that exhibit cationic pH-sensitive behavior as well as good water solubility. The copolymers are constructed by polymerization of tertiary amine methacrylate with either a (poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) polymer, such as the commercially available Pluronic( polymers, or a poly(ethylene glycol) polymer. The polymers may be use for drug and gene delivery, protein separation, as structural supplements, and more.

Advantage:
• These copolymers are water-soluble, pH sensitive and capable of thermoreversible gelation near physiological temperatures.
Application:
* Drug delivery * Gene delivery * Protein separation * Structural supplements
Patent Information:
*To see the full version of the patent(s), follow the link below, then click on "Images" button.
Country Serial No. Patent No. Issued Date
United States 10/366,864 7,217,776* 5/15/2007


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