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Direct Synthetic Route for Echinacea Compounds (Ynamides)
Category(s):
For Information, Contact:
Craig Forney
Commercialization Manager, Chemistry and Materials Sciences
515-294-4740
licensing@iastate.edu
Web Published:
5/15/2015
ISURF #
3089
Development Stage:
Description:
Researchers at Iowa State University have developed a direct synthetic route for diacetylenic amides, a type of ynamide, found in the plant Echinacea angustifolia. Echinacea angustifolia is an herb that is used worldwide for ailments such as colds, influenza, infections, laryngitis, and stings, as well as being an immunostimulant for cancer and AIDS. Some of the diacetylenic amides from Echinacea angustifolia have been found to be active against Aede aegypti larvae, a mosquito that carries Yellow fever and Dengue fever, and neonates of Helicoverpa zea, a corn bollworm.

Advantage:
• Currently the diacetylenic amides can only be obtained as a mixture of ynamides by extraction. By synthesizing the individual compounds their specific properties and activities can be determined as well as providing a new and purer way to fulfill the demand for Echinacea angustifolia products.

Application:
Dietary supplement based on Echinacea angustifolia. * New pharmaceuticals based on compounds found in Echinacea angustifolia. * Pesticide for Helicoverpa zea corn bollworms. * Insecticide for Aede aegypti mosquitoes.
Patent Information:
*To see the full version of the patent(s), follow the link below, then click on "Images" button.
Country Serial No. Patent No. Issued Date
United States 11/092,333 7,183,432* 2/27/2007


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