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"Healthy Beef": Fatty Acid Synthase Genetic Markers Associated with a Healthier Fatty Acid Composition
Category(s):
For Information, Contact:
Dario Valenzuela
Senior Commercialization Manager, Life Sciences
515-294-4740
licensing@iastate.edu
Web Published:
5/4/2015
ISURF #
3499
Summary:
The amount of saturated and unsaturated fat in meat and dairy products is of significant interest because of their implications for human health, and in particular, the relationship between consumption of saturated fat and cholesterol levels.  ISU researchers have recently developed a genetic marker for identifying cattle that have a more healthful fatty acid composition.

Development Stage:
Commercial feasibility has been demonstrated, and  Iowa State University is seeking partners for non-exclusive licensing of this technology.

Description:
Research has shown that human consumption of large amounts of saturated fats in foods such as meat can lead to heart disease.  ISU researchers investigating the bovine fatty acid synthase (FAS) gene have recently determined that the percentage of saturated fatty acids and the atherogenic index are associated with small genetic differences in the FAS gene.   Several single nucleotide polymorphisms (SNPs) were identified and a method was developed to identify these genetic markers.  This method has the potential to be a useful tool to genetically predict the fatty acid composition of beef or milk. In addition, the development of improved breeds could be accelerated since young animals can be tested before the meat or milk was harvested.

Advantage:
• Enables accelerated selection of cattle for “heart healthier” meat and dairy products compared to traditional breeding methods.
Application:
Rapid genetic selection of breeding stock with a lower atherogenic index and higher levels of healthier monounsaturated fatty acids

References:
Patent Information:
*To see the full version of the patent(s), follow the link below, then click on "Images" button.
Country Serial No. Patent No. Issued Date
United States 12/177,436 7,910,308* 3/22/2011


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