Latest technologies from Iowa State Universityhttp://isurftech.technologypublisher.comBe the first to know about the latest inventions and technologies available from Iowa State Universityen-USThu, 23 Nov 2017 06:27:38 GMTThu, 23 Nov 2017 06:27:38 GMThttp://blogs.law.harvard.edu/tech/rsssupport@inteum.comCopyright 2017, Iowa State UniversityImproved Synthetic Knee Joint Apparatus and Related Educational Methods for Clinical Knee Joint Examinationshttp://isurftech.technologypublisher.com/technology/26592Summary:
The synthetic knee model provides a teaching device for learning and simulating clinical examination of a patient's knee for the purpose of diagnosing damage to the anterior cruciate ligament (ACL), as well as damage to the meniscus. The synthetic knee model includes artificial skin,which looks and feels human-like. Orthopedic surgeons and certified athletic trainers have used the synthetic knee model, and given positive feedback. The practitioners that have used the synthetic knee model have tried it, like it, and want to add it to current curriculums.

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Description:
The synthetic knee model is capable of mimicking an intact ACL, partially torn ACL, and completely torn ACL. The synthetic knee model could provide medical students, physical therapy students, and athletic training students a device to practice the Lachman test, without fear of harm to the patient. The synthetic knee model would allow student practitioners to manipulate the knee, and become proficient at the Lachman test prior to performing the test on actual patients. The synthetic knee model is also capable of simulating varying types of meniscus damage, to aid in student learning. The synthetic knee model is easily transported, requires minimal space for learning, and offers a safe learning environment for students.

Advantage:
• Practice Lachman test on teaching model, not patients
• Can mimic varying integrities of ACL injury
• Can mimic varying types of meniscus injury
• Can be incorporated into variety of health professions curriculums
• Provide learner-conducive environment
• Easily transported and requires minimal space for learning

Patent:
Patent(s) applied for

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Tue, 14 Nov 2017 11:25:43 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/2659270002Tue, 14 Nov 2017 11:25:43 GMTSummary:

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]]>Patent:Patent(s) applied forDesc0000.pngJackHartwigsenjackh1@iastate.eduMedical DevicesFalseMagnetic two-way valves for paper based microfluidics: pathway for multi-step assayshttp://isurftech.technologypublisher.com/technology/26576Summary:
ISU researchers developed a paper-fluidic valve that can reversibly switch fluid delivery into multiple channels with controlled volume and/or frequency. In terms of electric circuit equivalence, this valve is akin to a transistor or an SPDT relay, hence enables programmable fluid delivery.

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Description:
Point-of-care diagnostics are an area of emerging interest for many health-care applications, particularly in-home or personalized care. Paper microfluidic lab-on-a-chip technologies have attracted a lot of attention in this area due to their low cost, with the assays often being disposable. Switching and gating mechanisms that are possible in many non-paper lab-on-a-chip technologies are not possible in the paper based analogues however, so new solutions have to be developed in order for functionality of these diagnostic tests to be similar to the more expensive tests. In paper microfluidics, the development of smart, reversible, and versatile switches is critical for the regulation of fluid flow across multiple channels.  Common limitations of current switches include long response times, limited switching capabilities, and irreversibility. A gating mechanism that is reversible, quick, and versatile is therefore interesting. To respond to this market need Iowa State University researchers have developed a paper-based microfluidic valve, capable of being switched between multiple channels in a reversible fashion.

Advantage:
• Reversible
• Cheap
• Fast acting
• Multichanneled
• Programmable
• Power-free

Application:
Microfluidics, sample preparation, purification, separation, diagnostics, ordering fluids schemes

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]]>Fri, 10 Nov 2017 11:38:34 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/265764675Mon, 13 Nov 2017 10:27:24 GMTSummary:

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]]>Application:]]>Desc0000.pngMarkJuettenAssociate Commercialization Manager, Chemistrymjuetten@iastate.eduFalseLogarithmic Photo-Converter with Huge Dynamic Rangehttp://isurftech.technologypublisher.com/technology/26090Summary:
This device is capable of measuring optical light levels that may vary from the single photon level up to many orders of magnitude larger illuminations. In fact, the upper range can be almost, apart from practical spatial details, as large as one desires. This device is possible due to the fact that the SiPMs can be exposed to daylight at full voltage without damage.

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Description:
Light sources that fluctuate by huge factors, from single photons up to 106 to 109 photons, are not common but do occur in the forward regions of particle colliders. They may also occur in bioluminescent materials over slower times scales, and possibly in optical measurements in non-destructive evaluation where the light level is varied over orders of magnitude to assess damage to a material.

For a very luminous light source, the choice is between a photo-detector that is sensitive to single photos but saturates above 100-to-1000 photos, or a photo-detector that attenuates the incident light in order to measure high light levels but which is therefore insensitive to single photons and low light levels.

This device, a "logarithmic photo-converter with huge dynamic range" is simultaneously sensitive to single photons and to arbitrarily large light levels. The dynamic range can be chosen at manufacture.

Advantage:
• Simultaneously sensitive to single photos and to arbitrarily large light levels
• Dynamic range can be calibrated after manufacture
• Input light does not have to be filtered or modified
• Accepts all incident light

Application:
Applications where measuring optical light levels may vary from the single photon to many orders of magnitude larger illuminations.

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]]>Fri, 25 Aug 2017 15:10:56 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/260904612Mon, 13 Nov 2017 10:26:58 GMTSummary:

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For a very luminous light source, the choice is between a photo-detector that is sensitive to single photos but saturates above 100-to-1000 photos, or a photo-detector that attenuates the incident light in order to measure high light levels but which is therefore insensitive to single photons and low light levels.

This device, a "logarithmic photo-converter with huge dynamic range" is simultaneously sensitive to single photons and to arbitrarily large light levels. The dynamic range can be chosen at manufacture.]]>Advantage:

]]>Application:Applications where measuring optical light levels may vary from the single photon to many orders of magnitude larger illuminations.Desc0000.pngJayBjerkeCommercialization Manager, Engineeringjbjerke@mail.iastate.edu515-294-4740FalseQuadruple Butterfly Coil (QBC)http://isurftech.technologypublisher.com/technology/26355

Summary:
Iowa State University researchers have developed a novel coil, namely Quadruple Butterfly Coil (QBC). This device has improved significant higher focality over the commercial Figure of Eight (FOE) coils with decreased stimulated area in brain. Model simulation results indicated that QBC stimulates a localized area of the brain, which minimized the stimulation of surrounding neural networks.

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Description:
Transcranial Magnetic Stimulation (TMS) is a widely used technique for the investigation of stimulation responses of the brain which has proven to have therapeutic effects for neurological disorders such as traumatic brain injury, Parkinson’s disease and post-traumatic stress disorder (PTSD). There have been many coils designed in the last twenty years due to TMS’ popularity, but no coils have shown significant improvement in focality over the commercial Figure of Eight (FOE) coils, while maintaining the field intensity required to stimulate at the depth of the surface of the brain.

Iowa State University researchers designed a new coil, Quadruple Butterfly Coil (QBC) with an improved double coil with two sets of coils. This new coil achieved a finer resolution for stimulation, with decreased stimulation volume over the cortex, while without deeper brain stimulation. QBC has been compared with commercial FOE coils using 50 anatomically realistic heterogeneous MRI derived head models, and results shows QBC has a significant improvement in focality over FOE with decreased stimulation area by approximately 1/3.

Lately, QBC performance for the application of Schizophrenic patients has been simulated at Magnetics Research Group at ISU. Preliminary results demonstrated the QBC provides a lightly weaker field, but has more focal over the FOE coils.  Specifically, the volume stimulated above 50% the local maximum was 30x greater in the FOE.

Advantage:
• Significantly higher focus of stimulation over the Figure of Eight (FOE) coils
• Smaller stimulated area by 1/3, with minimized stimulation of surrounding neural networks
• Decrease in Maximum induced E-field by about 50V/m
• QBC performance has been demonstrated via simulation for the application of Schizophrenic patients

Application:
This first major version of Quadruple Butterfly Coil (QBC) device can be used in neuromodulation market to improve therapeutic effects for neurological disorders patients.

References:
Transcranial Magnetic Stimulation-coil design with improved focality

Patent:
Patent(s) applied for

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]]>Wed, 04 Oct 2017 12:27:12 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/263554566Mon, 13 Nov 2017 10:26:36 GMTSummary:Iowa State University researchers have developed a novel coil, namely Quadruple Butterfly Coil (QBC). This device has improved significant higher focality over the commercial Figure of Eight (FOE) coils with decreased stimulated area in brain. Model simulation results indicated that QBC stimulates a localized area of the brain, which minimized the stimulation of surrounding neural networks.

]]>Stage3.pngDevelopment Stage:Description:Transcranial Magnetic Stimulation (TMS) is a widely used technique for the investigation of stimulation responses of the brain which has proven to have therapeutic effects for neurological disorders such as traumatic brain injury, Parkinson’s disease and post-traumatic stress disorder (PTSD). There have been many coils designed in the last twenty years due to TMS’ popularity, but no coils have shown significant improvement in focality over the commercial Figure of Eight (FOE) coils, while maintaining the field intensity required to stimulate at the depth of the surface of the brain.

Iowa State University researchers designed a new coil, Quadruple Butterfly Coil (QBC) with an improved double coil with two sets of coils. This new coil achieved a finer resolution for stimulation, with decreased stimulation volume over the cortex, while without deeper brain stimulation. QBC has been compared with commercial FOE coils using 50 anatomically realistic heterogeneous MRI derived head models, and results shows QBC has a significant improvement in focality over FOE with decreased stimulation area by approximately 1/3.

Lately, QBC performance for the application of Schizophrenic patients has been simulated at Magnetics Research Group at ISU. Preliminary results demonstrated the QBC provides a lightly weaker field, but has more focal over the FOE coils.  Specifically, the volume stimulated above 50% the local maximum was 30x greater in the FOE.

]]>Advantage:Significantly higher focus of stimulation over the Figure of Eight (FOE) coils]]>Smaller stimulated area by 1/3, with minimized stimulation of surrounding neural networks]]>Decrease in Maximum induced E-field by about 50V/m]]>QBC performance has been demonstrated via simulation for the application of Schizophrenic patients

]]>Application:

]]>References:Transcranial Magnetic Stimulation-coil design with improved focality

]]>Patent:Patent(s) applied forDesc0000.pngJayBjerkeCommercialization Manager, Engineeringjbjerke@mail.iastate.edu515-294-4740FalseNovel exosome-based oligomeric alpha-synuclein protien biomarker discovery using the RT-QuIC assay platformhttp://isurftech.technologypublisher.com/technology/25425Summary:
ISU researchers have developed an assay for following the progression of parkinsonain disorders.

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Description:
Parkinson's disease (PD) is a major neurodegenerative disorder affecting around 2% of the elder population in U.S, and its incidence is expected to rise dramatically with the advancing median age of the population. There are no current diagnostic tests or biomarker(s) to follow its progression. Current diagnosis and followup are mainly based on a thorough clinical history and neurological evaluation. ISURF #04583 is a method of use for RT-QuIC assay with remarkable accuracy targeting specifically Parkinson's disease (PD) and other parkinsonian disorders. Iowa State University researchers have demonstrated this technique to be rapid, sensitive, specific, and quantitative. The method is flexible, able to adopt to a variety of easily accessible samples including, but not limited to, body fluids like blood and urine. Thus far the researchers have demonstrated capability of detecting Mn poising (strongly linked to PD) in welders, a common occupational hazard.

Advantage:
• Fast
• Effective
• Selective

Application:
Identification and quantified tracking of Parkinson's disease and the family of Parkinsonian disorders.

Patent:
Patent(s) applied for

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]]>Fri, 02 Jun 2017 10:04:15 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/254254583Mon, 13 Nov 2017 10:26:13 GMTSummary:

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]]>Application:Identification and quantified tracking of Parkinson's disease and the family of Parkinsonian disorders.Patent:Patent(s) applied forDesc0000.pngMarkJuettenAssociate Commercialization Manager, Chemistrymjuetten@iastate.eduHealthcare| Life Sciences| Medical DevicesFalseElectrokinetic route to a wearable device for kidney disease managementhttp://isurftech.technologypublisher.com/technology/24013Summary:
ISU researchers have developed a technology that would allow for miniaturized dialysis by eliminating the need for the large dialysate reservoirs currently required.

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Description:
1.3 million patients world-wide have chronic kidney failure that requires treatment with dialysis or organ transplantation. Hemodialysis attempts to replace the role of functioning kidneys by removing excess fluid, salt, and waste products, such as urea. Traditional dialysis removes waste products from blood by passing it into a dialysate liquid through a molecular weight cutoff filter. This dialysis traditionally requires large immobile equipment and the treatment is often administered in the hospital or satellite hemodialysis units. A portable option, the wearable artificial kidney (WAK),  for dialysis has recently become available that would allow for more frequent treatment, and treatment that is easier to do at home while also improving the quality of life for patients who require frequent dialysis. However even the wearable units available still require large liquid reservoirs of dialysate to be attached. Replacing these reservoirs would be a key factor in further miniaturization. ISURF #04547 proposes a new dialysis supplementary device that removes the requirement for a dialysate reservoir. The device uses ion concentration polarization and downstream processing to source dialysate from excess fluid in the patient’s own blood.

Advantage:
• Allows for easier at home dialysis care
• No bulky dialysis reservoir needed

Patents:
Patent(s) Applied For

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]]>Thu, 09 Feb 2017 13:41:50 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/240134547Mon, 13 Nov 2017 10:25:42 GMTSummary:

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]]>Advantage:]]>Patents:Patent(s) Applied ForDesc0000.pngMarkJuettenAssociate Commercialization Manager, Chemistrymjuetten@iastate.eduMedical DevicesFalseHigh-Throughput selective capture of biological cells by dielectrophoresis at a bipolar electrode arrayhttp://isurftech.technologypublisher.com/technology/23519Summary:
ISU researchers have developed a device that employs an array of > 1,400 wireless electrodes for the continuous high-throughput isolation of cells that often are expressed in small concentrations.

Description:
ISURF #04548 describes an array of > 1,400 wireless bipolar electrodes (BPEs) in dielectrophoresis (DEP) devices. This allows for a large volume of cells to quickly be sorted based on dielectrophoric response. Without ohmic contact to the individual array elements, capacitive charging of the electrical double layer at opposing ends of each BPE allows an AC electric field applied by only two driving electrodes to be transmitted across the entire device. The electric field distribution is readily tuned by altering the dimensionality of BPEs. A suggested use of this technology is for detecting the presence of circulating tumor cells (CTC), which can be expressed as low as 1 in a billion cells, and that current technologies fall short of being able effectively diagnose, resulting in false negatives of patients in remission. ISU researches have thus far shown promising results of separating out breast cancer cells from white blood cell fractions.

Advantage:
• DEP separation allows for good sensitive and high specificity
• Wireless technology allows for new architectures and large arrays
• High throughput of cell

Application:
Cell capture and seperation

Patent:
Patent(s) applied for

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]]>Tue, 15 Nov 2016 14:08:09 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/235194548Mon, 13 Nov 2017 10:25:12 GMTSummary:

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]]>Patent:Patent(s) applied forStage1.pngDevelopment Stage:Desc0000.pngMarkJuettenAssociate Commercialization Manager, Chemistrymjuetten@iastate.eduFalseMethod of Controlled Drug Release from Nano-Patterned Polymer Stents Applicable to Cardiac Therapieshttp://isurftech.technologypublisher.com/technology/22742Summary:
ISU researchers developed a novel method to create nano-patterned stents that allow for a dramatic increase in drug release duration.

Description:
Two major problems of stents are i) thrombosis or clotting of platelets and ii) restenosis - a narrowing of the artery after stent use. A common strategy to relieve thrombosis and restenosis is to utilize drug eluting stents, which are coated with anti-clotting medication. The drug is slowly released into the bloodstream. The medication relieves rejection of the implanted stents. ISU researchers have developed a novel method to control the release of medication from such drug eluting stents utilizing bio-degradable stent materials such as polymer poly (L-lactic acid) (PLLA), which is a candidate for polymer stents. A method to create nanoscale patterning (with sub micrometer pitch) on bio-compatible polymers using a robust transfer molding approach was developed. The release of the immunosuppressant drug (sirolimus or rapamycin) from patterned and unpatterned (flat) polymer surfaces was measured. Significantly slower release rates (10-30%) were observed from nano-patterned surfaces than from flat surfaces.

Advantage:
• Up to 30% slower release
• Robust / Highly reproducible
• Can deliver numerous medications
• May have broader uses beyond stents

Application:
Cardiac Therapies

References:
Nanoscale patterning of biopolymers for functional biosurfaces and controlled drug release, Akshit Peer, Rabin Dhakal, Rana Biswas, and Jaeyoun Kim, Nanoscale, 2016, 8, 18654-18664, DOI: 10.1039/C6NR05197A

Patent:
Patent(s) applied for

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]]>Thu, 25 Aug 2016 15:18:13 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/227424494Mon, 13 Nov 2017 10:25:01 GMTSummary:

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]]>References:Nanoscale patterning of biopolymers for functional biosurfaces and controlled drug release, Akshit Peer, Rabin Dhakal, Rana Biswas, and Jaeyoun Kim, Nanoscale, 2016, 8, 18654-18664, DOI: 10.1039/C6NR05197A

]]>Patent:Patent(s) applied forStage2.pngDevelopment Stage:Desc0000.pngJayBjerkeCommercialization Manager, Engineeringjbjerke@mail.iastate.edu515-294-4740Healthcare| Medical DevicesFalseFeed Forward Automatic Insulin Delivery Systemhttp://isurftech.technologypublisher.com/technology/21067Summary:
Researchers at Iowa State University have developed a feedforward control system for Type 1 Diabetes management. Feedforward control systems, while requiring a more exhaustive model to be properly implemented, can provide better control than typical feedback systems. Moreover, the technology involves non-invasive techniques to manage insulin levels in the body, in contrast to feedback control systems which would require continuous monitoring of blood glucose concentration.

Description:
The technology aims to develop a feedforward control mechanism for Type 1 Diabetes treatment that utilizes a proprietary sensor approach for predicting blood glucose concentration using noninvasive inputs. The system is trained for each individual; the patient is monitored for a period of several weeks after which automatically collected data is analyzed and parameters are input into the model.

Advantage:
• Feedforward control system anticipates changes in blood glucose
• Non-invasive monitoring
• Highly customizable for each individual patent
• Tighter control parameters than attainable with traditional monitoring

Application:
Blood glucose management

Patent:
Patent(s) applied for

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]]>Tue, 08 Dec 2015 08:45:18 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/210674323Mon, 13 Nov 2017 10:23:42 GMTSummary:

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]]>Patent:Patent(s) applied forStage2.pngDevelopment Stage:Desc0000.pngCraigForneyCommercialization Manager, Chemistry and Materials Sciencesceforney@iastate.edu515-294-4740Medical DevicesFalseDroplet Actuator and Methods of Droplet Manipulationhttp://isurftech.technologypublisher.com/technology/21034Summary:
Iowa State University researchers have developed a portable system to perform droplet operations such as transport, mixing, merging, dispensing, and particle separation from liquid droplets. The system uses two electrical motors to tilt a planar platform at pre-specified angles, thereby allowing multiple droplets to move in pre-decided patterns.

Description:
The invention is a portable system to perform droplet manipulations such as transport, mixing, dispensing, and particle separation from liquid droplets.  The novelty is in the methods of moving droplets using gravitational force and mechanical jerks.  The design of hydrophilic patterns, along with the gravitational and mechanical tilting of the platform, help move the droplets.  The utility of this invention is the ease of use and low-cost compared to the existing technology being used today.  This system can help automate a diverse range of applications in molecular diagnostics of physiological samples.

Advantage:
• Portable, cost efficient design compared to currently available automated liquid handling systems
• Uses mechanical jerks and gravity to move droplets vs. current systems which use high electrical voltages, laser beams or vibrations from sound generating devices
• Utilizes unique techniques of printing patterns of specific shapes and sizes on a low-cost transparency film that has been treated to provide hydrophobic and hydrophilic areas

Application:
Immunology, protein chemistry, biomarker identification and molecular diagnosis of physiological samples

Patent:
Patent(s) applied for

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]]>Mon, 07 Dec 2015 11:38:08 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/210344313Mon, 13 Nov 2017 10:23:21 GMTSummary:

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]]>Patent:Patent(s) applied forStage2.pngDevelopment Stage:Desc0000.pngJayBjerkeCommercialization Manager, Engineeringjbjerke@mail.iastate.edu515-294-4740FalseMicroscale Tentacle Actuatorhttp://isurftech.technologypublisher.com/technology/21029Description:
ISU researchers have invented a soft material-based manipulator for delicate, fragile microscale objects. It is based on a thin-walled elastomeric microtube with an asymmetric wall thickness distribution and one end closed. Upon applying air pressure from the open end, the microtube becomes elongated non-uniformly, bending towards the thick-walled side. This type of bending, however, is often insufficient to induce a spiraling which mimics the coiling motion of biological tentacles, such as those of the octopus. To amplify the bending into multi-turn spiraling, we installed a small extra thickness (i.e., hump) to the exterior of the microtube. When the size and position of the hump were adequate, the microtube could accomplish multi-tum spiraling which is ideal for winding around small objects and scoop them up. This type of conformal spiraling motion is non-destructive since it does not involve squeezing and will be useful for safe handling of cell aggregates, eggs, or biological tissues that are highly fragile.

Advantage:
• Can handle soft, fragile micro-objects that is not offered today
• Capable of grabbing objects as small as ~ 185 µM with a grabbing force of ~ 0.78 mN
• Unique fabrication techniques of the thin, highly deformable microtubes

Application:
Biological microelectromechanical systems (bio-MEMS)

References:
Microrobotic tentacles with spiral bending capability based on shape-engineered elastomeric microtubes


Patent:
Patent(s) applied for

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]]>Mon, 07 Dec 2015 10:17:50 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/210294387Mon, 13 Nov 2017 10:23:17 GMTDescription:

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]]>Application:

]]>References:Microrobotic tentacles with spiral bending capability based on shape-engineered elastomeric microtubes

]]>Patent:Patent(s) applied forStage2.pngDevelopment Stage:Desc0000.pngJayBjerkeCommercialization Manager, Engineeringjbjerke@mail.iastate.edu515-294-4740FalseTriple Halo Transcranial Magnetic Stimulation Coilhttp://isurftech.technologypublisher.com/technology/21028Description:
Transcranial Magnetic Stimulation (TMS) is a non-invasive, safe method for the treatment of neurologic disorders such as depression, Post-Traumatic Stress Disorder, and Parkinson's disease. Currently, TMS is FDA approved for the treatment of depression.  The existing commercial TMS coils can only stimulate the cortical regions of the brain. For the success of the treatment of other neurological disorders, there is a need for the development of TMS coils that can stimulate deeper regions of the brain. Development of deep brain stimulation coils is challenging as the magnetic field decays rapidly with the distance from the source (coil surface). Magnetic fields with sufficient magnitude to stimulate the deeper regions of the brain should not stimulate the scalp of the patients. ISU researchers have developed a novel coil design based on our earlier "Halo Coil" configuration. This design of the new coil called the "Triple Halo Coil" will be able to stimulate deeper regions of the brain.

Advantage:
• The first of its kind that could potentially be used for the treatment of deep brain disorders non-invasively, safely and in an out-patient setting
• Capable of stimulating deeper regions of the brain with more than 10 times the magnetic field for the same amount of surface field at a depth of 10 cm
• Coils have been configured such that they do not overstimulate any part of the brain surface
• Electric and magnetic fields were calculated in heterogeneous head models

Application:
Health care. Transcranial Magnetic Stimulation.

Patent:
Patent(s) applied for

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]]>Patent:Patent(s) applied forStage1.pngDevelopment Stage:Desc0000.pngJayBjerkeCommercialization Manager, Engineeringjbjerke@mail.iastate.edu515-294-4740FalseSSM Sequence Modelshttp://isurftech.technologypublisher.com/technology/19750Description:
The SSM Sequence Models (SSMs) provide a mechanism for analyzing information and the relationships that may exist for that information in a much more computationally efficient manner than any current mechanisms in use today.  In its simplest terms, the SSMs can provide a spell checker that can identify a misspelled word and provide the correct spelling of the actual intended word.  In some of its more complex uses, the SSMs can provide voice recognition and speech synthesis, robotic learning using associative and auto associative memory, object recognition, Internet searching and categorization of information, and methods of recognizing, classifying, and analyzing biological sequences such as protein and DNA sequences–all with very high accuracy–to name a few.  Indeed, SSMs may be used in any application that currently use Hidden Markov Models (HMMs), and will provide these systems with an increase in speed and accuracy, and a decrease in the computing power that is needed to accomplish the specific task.  Further, unlike HMMs that often must be trained off line due to their computational complexity (particularly as the sequences involved become large), the SSMs can be trained in real time.  Simply put, SSMs are much more efficient and effective than HMMs in performing all of the tasks for which HMMs are currently used, and therefore provide an elegant replacement.

Advantage:
• Highly accurate and efficient
• Reduces computing power required for completing analysis
• Trainable in real-time
• Parallelizable

Application:
Pattern or Sequence Recognition Applications Including, but Not Limited to, Voice Recognition, Objection Recognition, Computational Biology, Robotic Learning, Search, and Classification

Patent:
Patent(s) applied for

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Development Stage:
A prototype implementation for speech recognition demonstrating high accuracy and reduced computing power has been completed.

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]]>Thu, 11 Jun 2015 13:19:45 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/197503990Mon, 13 Nov 2017 10:22:45 GMTDescription:

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]]>Desc0000.pngJayBjerkeCommercialization Manager, Engineeringjbjerke@mail.iastate.edu515-294-4740FalsePiezoelectric-Based Vibration Energy Harvesterhttp://isurftech.technologypublisher.com/technology/19689Summary:
The invention converts ambient vibrations into electrical form as a potential means of extending battery life.  Because of its bistable transduction and synchronized extraction, there has been a ~100X increase in harvested power, especially for broadband variations compared to other harvesters using the same input.


Description:
A potential means of extending battery life is the use of miniature renewable self-contained power supply units, which can convert ambient vibrations from existing sources in their environment into electrical form, and use this harvested energy to supplement batteries and/or other energy storage elements.  This invention employs a unique nonlinear, self-tuning, bistable vibration energy harvester capable of harvesting energy from broadband and varying-amplitude sources, combined with synchronized energy extraction circuits using electronic breaker switches for efficient harvesting.

Advantage:
• Extends battery life by effectively converting ambient vibrations into electrical energy
• Combines nonlinear bistable transduction with synchronized extraction
• Piezoelectric harvester with a simple micro-engineered design allowing a variety of material choices for ease of implementation
• ~100X increased harvested power, especially for broadband variations, compared to other harvesters using the same input, due to bistable transduction and synchronized extraction
• Presents a completely mechanical, zero-energy-cost method to increase range of excitation amplitudes over which the system remains bistable, further doubling the efficiency over varying amplitude excitations
• Presents for the first time an accurate mathematical model for a bistable transducer by augmenting the Butterworth van Dyke piezoelectric model to capture external magnetic forces

Application:
Remote sensors that can harvest ambient mechanical vibrations/energy to extend their battery life.

References:
Conference proceedings:  “Piezoelectric-based Broadband Bistable Vibration Energy Harvester and SCE/SSHI-based High-Power Extraction”, Kanishka Aman Singh, Ratnesh Kumar and Robert J. Weber, 11th IEEE International Conference on Networking, Sensing and Control, Miami, FL

Journal publication: “A Broadband Bistable Piezoelectric Energy Harvester with Nonlinear High-Power Extraction,” Kanishka Aman Singh, Ratnesh Kumar and Robert J. Weber, IEEE Transactions of Power Electronics, in press, accepted Dec 2014.

Patent:
Patent(s) applied for

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]]>Mon, 01 Jun 2015 12:02:35 GMTlicensing@iastate.eduhttp://isurftech.technologypublisher.com/technology/196894354Mon, 13 Nov 2017 10:21:52 GMTSummary:The invention converts ambient vibrations into electrical form as a potential means of extending battery life.  Because of its bistable transduction and synchronized extraction, there has been a ~100X increase in harvested power, especially for broadband variations compared to other harvesters using the same input.

]]>Description:

]]>Advantage:Application:

]]>References:Conference proceedings:  “Piezoelectric-based Broadband Bistable Vibration Energy Harvester and SCE/SSHI-based High-Power Extraction”, Kanishka Aman Singh, Ratnesh Kumar and Robert J. Weber, 11th IEEE International Conference on Networking, Sensing and Control, Miami, FL

Journal publication: “A Broadband Bistable Piezoelectric Energy Harvester with Nonlinear High-Power Extraction,” Kanishka Aman Singh, Ratnesh Kumar and Robert J. Weber, IEEE Transactions of Power Electronics, in press, accepted Dec 2014.

]]>Patent:Patent(s) applied forStage2.pngDevelopment Stage:Desc0000.pngJayBjerkeCommercialization Manager, Engineeringjbjerke@mail.iastate.edu515-294-4740False