Latest technologies from Iowa State Universityhttp://isurftech.technologypublisher.comBe the first to know about the latest inventions and technologies available from Iowa State Universityen-USWed, 22 May 2019 18:58:25 GMTWed, 15 May 2019 08:28:33 GMT 2019, Iowa State UniversityGene controlling spontaneous haploid genome doubling in maize, 15 May 2019 08:28:33 GMTlicensing@iastate.edu Haploid Genome Doubling Maize Donor Line, 15 May 2019 08:19:19 GMTlicensing@iastate.edu Monoclonal Antibodies for Diagnostics and Therapeutics, 10 May 2019 13:22:31 GMTlicensing@iastate.edu Enrichment Device for Poultry An invention where a laser device is used to stimulate the natural predatory and visual oriented instincts of poultry to hunt and chase bugs or other small moving objects. This is a better enrichment option for poultry producers to comply with guidelines to improve poultry health and welfare.Description: Current enrichment options to comply with guidelines to improve poultry health and welfare are physical barriers, including perches, mazes, straw bales, field tile and others. They may become biohazardous as the poultry can deposit bodily fluid or feces on, and then this becomes a poi...Fri, 03 May 2019 12:13:01 GMTlicensing@iastate.edu optimized nls-Mad7-nls for targeted double-strand breaks in vertebrates, 02 May 2019 09:47:20 GMTlicensing@iastate.edu Nanovaccine, 30 Apr 2019 14:17:19 GMTlicensing@iastate.edu Affecting Flowering Time in Maize, 16 Apr 2019 10:53:18 GMTlicensing@iastate.edu Isothermal Nucleic Acid Amplification Reaction Systems using Magnetic Ionic Liquids, 11 Apr 2019 12:09:52 GMTlicensing@iastate.edu Contact Lens for Intraocular Pressure Monitoring, Drug Release and Disease Biomarker Detection, 11 Apr 2019 11:58:28 GMTlicensing@iastate.edu efficient biobased transparent UV-blocking coatings fabricated using hydroxyethyl cellulose and ZnO nanoparticles, 09 Apr 2019 09:37:58 GMTlicensing@iastate.edu Ionic Liquids for Capture, Concentration, and Molecular Detection of Microbes, 26 Mar 2019 10:06:40 GMTlicensing@iastate.edu, surface modification and self-assembly of Au-Fe3O4 nano-dumbbells, 06 Mar 2019 13:41:25 GMTlicensing@iastate.edu for high frequency tracking and sub-nm sample stabilization in single molecule microscopy, 06 Mar 2019 09:08:10 GMTlicensing@iastate.edu of high-temperature iron-based superconductors ISU and UC-Davis scientists have developed a method for making iron arsenide superconductors via a spark plasma synthesis (SPS) method. Description: Iron-based superconductors are an attractive candidate for practical applications because of their low cost of materials and critical temperatures higher than 20K. Iowa State University and University of California, Davis scientists have developed a method for using a spark plasma synthesis method to make iron arsenide superconductors. BaFe2As2 superconductors doped with Co or Ni were synthesized by heat treatment of the reactive BaH2 pr...Mon, 25 Feb 2019 09:02:31 GMTlicensing@iastate.edu and Characterization of Porcine Sapelovirus Strain US/ISU26908B/18 This disclosure isolated a novel porcine sapelovirus (PSV) from a swine spinal cord sample. Description: Porcine Sapelovirus (PSV) is an emerging cause of atyptical neurological disease in swine resulting commonly in a herd mortality of 1-3%, and occasionally up to 10% on affected farms. Currently there is no purified cell-adapted PSV virus isolate reported obtained in the United States, so pathogenesis studies, genetic characterization, serological assays, in vitro characterization, and vaccine development are not available due to the lack of a PSV isolate. Our inventors developed a...Mon, 25 Feb 2019 08:40:58 GMTlicensing@iastate.edu ionic liquids as gas chromatography stationary phases, 18 Feb 2019 08:15:36 GMTlicensing@iastate.edu for water electrolysis ISU and Ames Laboratory scientists have developed a metal chalcogenide material for use as a water electrolysis catalyst for the generation of hydrogen. Description: Hydrogen is a unique energy carrier in that it can be produced from a number of diverse pathways utilizing a variety of domestically available feedstock, including natural gas, biomass, and water. The electrochemical splitting of water (electrolysis) is among the most versatile and greenest methods of hydrogen generation that will play a significant role in long-term, high-volume hydrogen gas production. Iowa State Unive...Thu, 14 Feb 2019 12:09:58 GMTlicensing@iastate.edu Synthetic Knee Joint Apparatus and Related Educational Methods for Clinical Knee Joint Examinations The synthetic knee model provides a teaching device for learning and simulating clinical examination of a patient's knee for the purpose of diagnosing damage to the anterior cruciate ligament (ACL), as well as damage to the meniscus. The synthetic knee model includes artificial skin,which looks and feels human-like. Orthopedic surgeons and certified athletic trainers have used the synthetic knee model, and given positive feedback. The practitioners that have used the synthetic knee model have tried it, like it, and want to add it to current curriculums. Stage3.png Development Stage: ...Mon, 11 Feb 2019 16:10:29 GMTlicensing@iastate.edu Elements in Enterococcus spp. to Produce Dopamine This disclosure provides a biotechnological approach to produce dopamine as well as a method to screen for probiotics. Description: In this disclosure, ISU researchers report the identification of a Enterococcus spp tyrosine decarboxylase gene and other genomic regions for the production of dopamine. Dopamine is a mammalian neurotransmitter of the CNS made from L-DOPA by L-DOPA decarboxylase and used as a therapeutic for the treatment of heart failure and shock, especially in newborn babies. The worldwide production of dopamine is in the hundreds of millions of dollars. That need is e...Mon, 28 Jan 2019 09:44:11 GMTlicensing@iastate.edu dimensional early transition metal carbides (MXenes) as catalysts for water gas shift and propane dehydrogenation researchers have developed a new catalyst for efficient conversion of carbon monoxide into carbon dioxide and hydrogen as part of the water gas shift reaction and transforming shale gas efficiently into propylene via propane dehydration. Description: 2D materials have unusual electron, mechanical and optical properties and have been extensively studied, particularly in the last twenty years, for a diversity of applications. The majority of these studies have focused on graphene; there have been far fewer investigation on non-carbon 2D materials. Typical 2D materials show improved properti...Wed, 16 Jan 2019 10:04:59 GMTlicensing@iastate.edu setups for high throughput screening of 3D printable resins ISU and Ames Laboratory scientists have developed an adapter that conserves the volume of resin used in the 3D printing of smaller parts. Description: Common commercial 3D-printers have a single build platform that requires a significant volume of material for every printing task, regardless of size of your target part. Consequently, screening different materials demands production of large amounts of resins. Furthermore, only one resin can be tested in a single run so testing multiple candidate resins is either time consuming or requires several costly printers operating in parallel...Mon, 07 Jan 2019 13:20:36 GMTlicensing@iastate.edu selective capture, sequestration, fluidic isolation, electrical lysis and analysis of single cells ISU researchers have developed a microfluidic platform capable of selective single-cell capture, isolation, and rapid electrical lysis for analysis. Description: Iowa State University researchers have developed a microfluidic device for selective single-cell capture at an array of wireless bipolar electrodes. Thus, selective cell isolation, retention, reagent exchange, fluidic isolation, and rapid electrical lysis can be accomplished for high-throughput analysis. This technology is tunable and can be broadly applicable to many cell types (and mixtures) and can be adapted to a wide va...Wed, 05 Dec 2018 09:06:02 GMTlicensing@iastate.edu paper-based assay for quntitation and identification of glycan and oligosaccharide sugars ISU researchers have developed a colometric paper assay, able to rapidly detect glycan linkages. Description: Viable synthetic human milk relies on development new methods of making the human milk olgiosaccharides (HMO) that are necessary for supplementing formula. New synthesis methods will require monitoring and analysis of the glycan (oligiosaccharide) products. Current analysis of glycans is limited in throughput and scope by the need for LC/MS technology, which can take roughly an hour for one sample, and requires expensive equipment, specialized columns and derivatizing agents,...Mon, 08 Oct 2018 10:07:03 GMTlicensing@iastate.edu La-Fe-Si Alloys for Magnetocaloric Applications, 25 Jul 2018 12:46:06 GMTlicensing@iastate.edu effective treatment to prevent freeze induced egg yolk gelation, 25 May 2018 13:33:55 GMTlicensing@iastate.edu, Low Cost, Non-Toxic Technology for PEF Polymer Production ISU researchers have demonstrated an inexpensive, commercially available material, as an effective catalyst for the disproportionation or isomerization of armatic carboxylates to dicarboxylates, allowing for new production routes to valuable polymers such as PET and PEF. Description: Dicarboxylic acids, such as terephthalic acid or 2,5- furandicarboxylic acid, are commonly used in polyesters such as polyethylene terephthalate (PET), the most common polyester (over 30 million tons produced per year). Polyethylene Furoate (PEF) is an emerging possible replacement to PET in part because...Thu, 24 May 2018 10:10:43 GMTlicensing@iastate.edu of Muconic Acid for the Production of Bio-based Terephthalic Acid, 21 May 2018 13:43:15 GMTlicensing@iastate.edu of methylammonium lead iodide perovskite films via cation exchange of melt-processed films for photovoltaic applications, 04 May 2018 14:49:12 GMTlicensing@iastate.edu, Cobalt and Copper Alloy doped with Tantalum or/and Iron as a Permanent Magnet Material ISU and Ames Laboratory researchers have develop a gap magnet that utilizes trace amount of cheaper, abundant and non-critical cerium (Ce) as an alternative to critical rare-earths containing magnet alloys. This invention makes the magnet significantly cheaper and less dependent on supplies of rare-earth materials, with that performance surpasses the levels of commercial ferrite and AlNiCo magnets, and approaches the performance of neodymium-based and samarium cobalt magnets. Description: Permanent magnets are broadly classified into four segments based on composition and magnet stre...Mon, 30 Apr 2018 10:48:53 GMTlicensing@iastate.edu M. hyorhinis polyprotein for vaccines and diagnostics, 02 Apr 2018 09:15:44 GMTlicensing@iastate.edu Intermetallics with Enhanced Magnetocaloric Properties Prepared by Combination of Different Methods Iowa State University (ISU) and Ames Laboratory (AL) researchers have developed a method to manufacture Ni-Co-Mn-Ti intermetallics with enhanced magnetocaloric properties. The resultant materials produce an extremely large magnetocaloric effect (MCE) with a modest magnetic field change. The MCE is nearly three times greater at near room temperature than the same material made via conventional processing. Description: Magnetocaloric materials undergo a change in temperature when subjected to the application and removal of a magnetic field. While a number of magnetocaloric materials ha...Tue, 20 Mar 2018 08:35:38 GMTlicensing@iastate.edu for Caloric Applications, 26 Feb 2018 13:02:54 GMTlicensing@iastate.edu levulinic acid to olefins and aromatics (i.e. hydrocarbon fuels) in a single process step without external hydrogen gas Iowa State University researchers have developed a new catalyst that effectively converts levulinic acid to butene in a single pot process at high conversion rates and with good selectivity towards butene. As butene is insoluble in the aqueous reaction and readily separates into a second phase, allowing unconverted levulinic acid to be readily recycled for re-processing, selectivity can be increased by changing reaction parameters towards lower conversion. The products obtained from this process contains mainly cyclic olefins and aromatics, which are ideal candidates for making gasoli...Wed, 21 Feb 2018 14:19:08 GMTlicensing@iastate.edu and Heterogeneous Structure for Tough Rare Earth Permanent Magnets and Production Process Thereof Iowa State University and Ames Laboratory researchers have developed a method for producing rare earth permanent magnets (REPMs) that reduces their susceptibility to breakage. The process involves unitizing a bimodal or multimodal size distribution of powders in isostatic pressing, which minimizes crack propagation along the grain boundaries of the magnet. This invention significantly enhanced flexural strength and fracture toughness while maintaining the hard magnetic properties. Description: Among three basic classes of permanent magnets, sintered magnets, bonded magnets and additi...Wed, 21 Feb 2018 13:41:50 GMTlicensing@iastate.edu Nanosensors for Hydrolytic Enzyme Characterization Iowa State University Researchers have developed a new biosensor for hydrolytic enzyme characterization based on single walled carbon nanotubes. Description: Single walled carbon nanotubes (SWNT) are becoming ubiquitous in chemical sensing applications. Able to fluoresce in the near-IR, with no photo-bleaching threshold, they are ideal for prolonged imaging in living cells and tissues. Although SWNT are usually insoluble in water, Iowa State University researches wrapped them in amphiphilic polymers, thereby solubilizing them. By destroying or altering this polymer wrapping, the SWNT...Fri, 09 Feb 2018 15:53:32 GMTlicensing@iastate.edu Carbon Fiber Precursors ISU researchers have developed a process to produce carbon fibers from cheap lignin precursors. Description: Carbon fibers have become a material of great interest due to their incredible structural properties while maintaining low weight. To date, the majority of carbon fibers are produced from polyacrylonitrile. Carbon fiber applications and markets have been restricted by the high cost of this petroleum-based feedstock. Lignin is a commonly suggested feedstock as a low cost alternative due to its existing highly aromatic character. However, thus far, carbon fibers drawn from ligni...Fri, 15 Dec 2017 12:50:08 GMTlicensing@iastate.edu Promoted in Heat Treatable Magnets Through Application of External Applied Magnetic Field at the Start of Binder-Assisted Molding, 20 Nov 2017 12:35:01 GMTlicensing@iastate.edu Butterfly Coil (QBC) Summary: Iowa State University researchers have developed a novel coil, namely Quadruple Butterfly Coil (QBC). This device has improved significant higher focality over the commercial Figure of Eight (FOE) coils with decreased stimulated area in brain. Model simulation results indicated that QBC stimulates a localized area of the brain, which minimized the stimulation of surrounding neural networks. Stage3.png Development Stage: Description: Transcranial Magnetic Stimulation (TMS) is a widely used technique for the investigation of stimulation responses of the brain which has proven to ...Wed, 04 Oct 2017 12:27:12 GMTlicensing@iastate.edu for Computing Casual Inference from Time Series Data Iowa State University researchers have developed a novel algorithm approach for computing causal interaction from time series data. The proposed approach will help determine which time series data will cause or influence which other time series data, given two or more-time series data. Stage1.png Development Stage: Description: The detection between cause and effect (causality) has long been a question in many scientific area. There are various theories developed so far, but they failed to give the causal structure in dynamic systems. Besides, none of these definitions is capable o...Wed, 27 Sep 2017 10:43:35 GMTlicensing@iastate.edu Photo-Converter with Huge Dynamic Range This device is capable of measuring optical light levels that may vary from the single photon level up to many orders of magnitude larger illuminations. In fact, the upper range can be almost, apart from practical spatial details, as large as one desires. This device is possible due to the fact that the SiPMs can be exposed to daylight at full voltage without damage. Stage2.png Development Stage: Description: Light sources that fluctuate by huge factors, from single photons up to 106 to 109 photons, are not common but do occur in the forward regions of particle colliders. They may a...Fri, 25 Aug 2017 15:10:56 GMTlicensing@iastate.edu treatment of gut inflammation, 09 Aug 2017 11:53:20 GMTlicensing@iastate.edu of pure or doped porous oxide materials through self-assembly of coordination polymerization, 25 Jul 2017 12:57:16 GMTlicensing@iastate.edu self-healing and self-strengthening polymer-metal composites Autonomously self-healing and self-strengthening polymer-metal composites developed at Iowa State University have the potential to impact many material markets. Description: Despite self-healing technology being available since 2001, there are limited commercial examples of self-healing materials. ISURF 04588 demonstrates the the application of undercooled particles in producing mechanically responsive and reconfigurable composites. The composite exploits the metastable nature of the particles, whereby the undercooled liquid metal trapped within the particles undergoes solidification...Tue, 25 Jul 2017 12:57:15 GMTlicensing@iastate.edu Influenzae Immunogen A powerful antigenic protein for the development of a vaccine against Nontypeable Haemophilus Influenzae Stage1.png Development Stage: Description: Nontypeable Haemophilus Influenzae (NTHI) is a significant respiratory pathogen associated with millions of yearly middle ear infections in young children and with many cases of pneumonia in the elderly. Currently, there is no efficacious vaccine against Nontypeable Haemophilus Influenzae. By comparing children prone to ear infections with non-prone children, the ISU contributors discovered that non-prone children differed from prone ch...Wed, 19 Jul 2017 12:25:39 GMTlicensing@iastate.edu tuber yield enhancement Inhibition of two potato genes can be used to produce plants with greater tuber yields without affecting plant growth. Stage1.png Development Stage: Description: Researchers from Iowa State University and the Indian Institute of Science Education and Research have jointly demonstrated increased tuber yields in potato by inhibiting the potato genes StBEL11 and StBEL29.Potato BEL1-like genes encode transcription factors that work in tandem with KNOTTED1-types to regulate the expression of many genes. Potato StBEL5 functions as a long-distance mRNA signal that is transcribed in leave...Wed, 12 Jul 2017 14:39:14 GMTlicensing@iastate.edu Correction in Spinal Muscular Atrophy by Targeting Intronic Sequences This technology has the potential to increase the Spinal Muscular Atrophy protein levels in patients with Spinal Muscular Atrophy. The innovation is a blocking antisense oligonucleotide and its target site located in a deep intronic sequence of the SMN2 gene. The blocking of the SMN2 target sequence corrects the defective splicing of the gene. Stage1.png Development Stage: Description: Humans possess two nearly identical copies of survival motor neuron (SMN) gene: SMN1 and SMN2. Loss of SMN1 coupled with the inability of SMN2 to compensate for loss of SMN1 causes spinal muscular atr...Wed, 21 Jun 2017 13:56:59 GMTlicensing@iastate.edu Enrichment of Viable Bacteria using Magnetic Ionic Liquids for PCR Amplification and Culture-Based Diagnostics ISU researchers have developed new molecules with an accompanying method to preconcentrate bacteria for rapid detection for food safety testing.Description: The detection of viable bacteria in food, environmental, or clinical samples is limited by time-consuming enrichment procedures (e.g., overnight cultures) that are often mandatory for the analysis of extremely small quantities of microorganisms. Iowa State University researchers have developed new molecules to act as magnetic ionic liquids (MILs) and an method of use thereof to isolate, extract, and concentrate bacteria in an effi...Fri, 02 Jun 2017 10:04:16 GMTlicensing@iastate.edu Metal-Metal Composite Conductor Summary: Iowa State University and Ames Laboratory researchers have developed a high strength, lightweight aluminum wire for high-voltage power transmission with reduced electrical resistance for overhead electrical lines. Description: High-voltage electric power transmission cables based on pure aluminum strands with a stranded steel core (ACSR) or stranded aluminum alloy (ACAR) core have the disadvantages of mediocre tensile strength, high density, and poor strength and conductivity retention at elevated temperatures. This combination of properties causes excessive sag in overload situati...Wed, 24 May 2017 14:03:36 GMTlicensing@iastate.edu of mixed metal chalcogenides by mechanochemical processsing and exfoliation, 24 May 2017 13:57:50 GMTlicensing@iastate.edu soil made by gel beads, 24 May 2017 13:57:50 GMTlicensing@iastate.edu anthelmintic drugs This invention includes two new anthelmintic compounds. The compounds are (S)-5-ethynyl-anabasine and (S)-5-bromoanabasine. These compounds are both derivatives of the nicotine molecule and are agonists of a nicotinic ACh receptor. This invention may take advantage of the large market for animal parasiticides and the lack of existing patented drugs for deworming. Stage2.png Development Stage: The current status of the invention is at the proof of concept stage. Description: Nematode parasites infect ~2 billion people world-wide and infections are treated and prevented by anthelmintic...Wed, 24 May 2017 13:57:49 GMTlicensing@iastate.edu Unit for Thermal Conductivity Measurements in Multiple Cryogenic/Magnetic Field Environments, 16 Feb 2017 10:11:13 GMTlicensing@iastate.edu transport in probiotics The discovery of the existence of a neurotransmitter transport mechanism in some probiotics is disclosed as well as a method to identify suitable probiotic strains with high potential to modulate neurotransmitter levels in an animal or human host. Stage2.png Development Stage: Description: Probiotics are designated as living microorganisms that may be used for both maintenance of health as well as treatment of specific clinical conditions ranging from gastrointestinal infections to the treatment of neuropsychiatric-related behavioral issues. Probiotics are also extensively used in t...Thu, 09 Feb 2017 14:10:49 GMTlicensing@iastate.edu (AZD0503) is a epilepsy treatment drug candidate, 09 Feb 2017 13:51:16 GMTlicensing@iastate.edu route to a wearable device for kidney disease management ISU researchers have developed a technology that would allow for miniaturized dialysis by eliminating the need for the large dialysate reservoirs currently required. Stage1.png Development Stage: Description: 1.3 million patients world-wide have chronic kidney failure that requires treatment with dialysis or organ transplantation. Hemodialysis attempts to replace the role of functioning kidneys by removing excess fluid, salt, and waste products, such as urea. Traditional dialysis removes waste products from blood by passing it into a dialysate liquid through a molecular weight cutoff...Thu, 09 Feb 2017 13:41:50 GMTlicensing@iastate.edu jejuni peptide for vaccine development A promising target for designing a diagnostic test and peptide sequence for vaccine development to control Campylobacter jejuni infections in ruminants and humans. Stage1.png Development Stage: Description: Campylobacter jejuni is a major causative agent for abortion in ruminants, particularly in sheep. It is also a major foodborne pathogen and a leading cause of enteritis in humans, responsible for 400-500 million cases of diarrhea annually worldwide each year. In the U.S. alone, C. jejuni accounts for more than 800,000 cases of foodborne illnesses each year. A hyper virulent clone...Tue, 31 Jan 2017 13:58:24 GMTlicensing@iastate.edu Protocol for Bovine Digital Dermatitis Lesions Using a Cocktail of Pure Growth Organisms, 31 Jan 2017 13:17:47 GMTlicensing@iastate.edu toxin delivery mediated by a densovirus coat protein A Junonia coenia densovirus coat protein with potential to create fusion proteins expressed in transgenic crops to control the fall armyworm. Stage1.png Development Stage: Description: The fall armyworm is a continuous resident of the Gulf States. Corn, sorghum, and other plants of the grass family are its preferred foods, but the fall armyworm also attacks alfalfa, bean, peanut, potato, sweet potato, turnip, spinach, tomato, cabbage, cucumber, cotton, tobacco, all grain crops, and clover. Each year the fall armyworm can be found as far north as Montana, Michigan, and New Hampshire....Tue, 31 Jan 2017 13:10:19 GMTlicensing@iastate.edu Engineered Membrane Proteins for Improved Membrane Integrity and Production of Fatty Acids in Escherichia coli, 21 Dec 2016 14:00:16 GMTlicensing@iastate.edu Mixed Network Former High Ion Conductivity Solid Electrolytes ISU researchers have developed a compound to replace the liquid electrolyte that is used in lithium ion batteries with a safer solid matrix for use in a sodium ion battery alternative. Stage2.png Development Stage: Description: Lithium ion batteries have become ubiquitous in our society, powering almost all cell phones, laptops, and electric and hybrid cars. The high power density and low weight has made these batteries attractive despite questionable stability. When these batteries fail, the results can be spectacular, including highly publicized catastrophic failures that result ...Fri, 16 Dec 2016 13:24:06 GMTlicensing@iastate.edu Dissolution and Separation of Rare-earth Metals ISU and Ames Laboratory researchers have developed a method to effectively recycle rare earth elements through simple REDOX reactions allowing for aqueous processing. This replaces the need for dangerous and environmentally unfriendly acids. Stage2.png Development Stage: Description: Rare earth elements (REE) have seen a sharp increase in use in a number of technical materials such as high density and high temperature tolerant permanent magnets, lamp phosphors, catalysts, rechargeable batteries and many other technologies related to a transition to a greener economy. With China cont...Fri, 16 Dec 2016 13:05:02 GMTlicensing@iastate.edu Methods Including: (1) Patterning of Nanophotonic Structures at Optical Fiber Tip For Refractive Index Sensing and (2) Plasmonic Crystal Incorporating Graphene Oxide for Detection of Gaseous/Aqueous compounds, 13 Dec 2016 12:09:55 GMTlicensing@iastate.edu Encapsulation of Ureolytic Bacteria for Self-healing of Cement-Based Composites, 13 Dec 2016 12:09:55 GMTlicensing@iastate.edu Soil Nutrient Sensor for Agriculture, 21 Nov 2016 10:57:44 GMTlicensing@iastate.edu paraffin-like coating materials from soybean oil, 15 Nov 2016 14:11:01 GMTlicensing@iastate.edu selective capture of biological cells by dielectrophoresis at a bipolar electrode array, 15 Nov 2016 14:08:09 GMTlicensing@iastate.edu Low Ash, Low Sulfur Coal Replacement from Fast Pyrolysis of Biomass ISU researchers have developed a process for taking phenolic oils from lignocellulosic biomass and curing them to obtain a coal substitute. Description: This technology involves the curing of phenolic oils derived from pyrolysis into a material suitable for combustion as a coal-supplement or as a coal replacement for steam generation. Stage Fraction 1 and 2 materials are processed by water washing to remove sugars and are subsequently heated by waste process heat to a hardened form. This cured and hardened material is then ground to a consistency comparable to coal and tested as a co...Fri, 07 Oct 2016 13:04:06 GMTlicensing@iastate.edu Cost and High Performance Fuel Cells Fed with Biomass-Derived Feedstock ISU researchers have developed a high performance low cost biomass fuel cell technology that can be directly fed with biomass wastes/residuals, biorefinery or pyrolytic streams as fuels. Description: This technology is a fuel cell that can transform biomass wastes into useable energy at low cost. The membrane, anode and cathode catalysts are all designed to lower the overall cost of the system while maintaining performance. The fuel cell is an anion exchange membrane type fuel cell which uses a low cost PTFE membrane. The anode catalyst is a non-precious metal or non-metal. The catho...Fri, 07 Oct 2016 13:04:06 GMTlicensing@iastate.edu Metal Secondary Battery, 07 Oct 2016 13:04:05 GMTlicensing@iastate.edu Dehydrogenation Catalyst with Greatly Enhanced Lifespan Iowa State University and researchers have developed a process to platinum-tin catalysts for propane dehydrogenation to enhance catalyst lifetime before regeneration up to six-fold. Description: Propane dehydrogenation is a common method to produce propylene, one of the most important chemical building blocks. Platinum-tin catalysts have been shown to have high selectivity towards propylene with good yield, but suffer from quick deactivation from coking. Iowa State researchers have discovered a treatment method that provides a six-fold increase in catalyst life before coking and deac...Tue, 13 Sep 2016 11:39:28 GMTlicensing@iastate.edu of Bt toxins to target Asian Citrus Psyllid for HLB treatment in citrus ISU researchers have identified several Cry toxins from the bacterium Bacillus thuringiensis (Bt) for the management of Asian Citrus Psyllid (ACP) and the associated HLB disease in the citrus industry. Description: The Asian citrus psyllid (ACP, Diaphorina citri Kuwayama) is an important pest of citrus in several countries. ACP can transmit bacterium, Candidatus Liberibacter asiaticus, which causes a devastating citrus disease called huanglongbing (HLB), also known as citrus greening disease. The disease destroys citrus trees in many countries and states, including Florida. It is est...Fri, 09 Sep 2016 12:13:14 GMTlicensing@iastate.edu Gene Fragment Assembly ISU researchers have developed a method that can assembly up to 45 fragments into a full-length gene sequence with only two steps, the assembly step and the PCR step. Description: Gene synthesis technology, in contrast to gene engineering, is a method in synthetic biology that is used to create genes de novo. It has become a powerful tool in many fields of recombinant technology including gene therapy, vaccine development and molecular engineering. Current approaches are mostly based on a combination of organic chemistry and molecular biological technique, and requires multiple step...Thu, 25 Aug 2016 15:08:56 GMTlicensing@iastate.edu Novel Vegetable Oil-Based Material as Substitute for Carnauba Wax ISU researchers have developed a synthetic process to convert soybean oil into a new material with a high hardness comparable to that of palm-based carnauba wax and a much higher melting point. Description: In North America, the consumption of wax is around three billion pounds per year with an associated vale in excess of three billion dollars. Markets of waxes are diverse, ranging from simple fuel in candles to practical applications such as coating in the paper and packaging industry. The largest market of wax remains in the packaging area, which are mostly derived from petroleum-...Thu, 28 Jul 2016 12:19:44 GMTlicensing@iastate.edu Muscular Atrophy: A streamlined reporter system to screen for therapeutic compounds ISU researchers have developed a reporter system based on an abbreviated version of the SMN2 gene to screen potential therapeutic compounds involved in the transcription, splicing and translation of SMN2. Description: Pre-mRNA splicing is a complex molecular process involving RNA transcription, 5' and 3'-end RNA processing, and multiple RNA processing proteins. Humans have two nearly identical copies of the Survival Motor Neuron (SMN) gene: SMN1 and SMN2. Skipping of SMN2 exon 7 during pre-mRNA splicing results in a truncated SMN2 transcript which is quickly destroyed inside the cell...Wed, 06 Jul 2016 10:18:11 GMTlicensing@iastate.edu Sensitivity MEMS Pressure Sensor, 14 Jun 2016 11:05:37 GMTlicensing@iastate.edu of a Printable Graphene using Pulsed Laser Annealing for Electrochemical Sensing and Biosensing, 03 Jun 2016 13:19:29 GMTlicensing@iastate.edu Wearable Microwave Meta-Skin with Tunable Frequency and Cloaking Effects, 03 Jun 2016 13:19:28 GMTlicensing@iastate.edu of Enhanced AlNiCo Magnets ISU and Ames Lab researchers have developed a method for producing AlNiCo magnets that employs the substitution of less expensive materials for cobalt in the AlNiCo alloy. Description: AlNiCo magnets account for a little more than four thousand metric tons of material with a market value of $280mn. AlNiCo magnets are often used as a replacement magnet for ferrite magnets when high temperature performance is required. Raw materials are estimated to account for approximately 33% of the cost of AlNiCo magnets, with the most expensive element being cobalt. The technology involves the sub...Thu, 26 May 2016 11:16:24 GMTlicensing@iastate.edu Method to Create Ultra-flat Metal Surfaces ISU researchers have developed a method to produce ultra-flat metal surfaces without the compromises inherent to chemical-mechanical polishing (CMP). Description: Ultra-flat surfaces are important commercially for the semiconductor fabrication industry, and also are of interest for scientific studies of self-assembled monolayers, bilayers, electrodes and single-molecules. There are several methods to create ultra-flat surfaces including CMP which is the most common method currently used but is often a method of compromises, attempting to balance material removal rate against the susc...Thu, 05 May 2016 13:14:24 GMTlicensing@iastate.edu Protein Synthases for the Production of Bi-Functional Fatty Acids ISU researchers have developed biocatalysts that make bi-functionalized molecules (fatty acids) and a recombinant bacterial expression system.Description: Fatty acids normally synthesized in biological systems have only one functional group, carboxylic acid, which is found at the alpha end of the molecule. Bi-functional fatty acids, where there is also a functional group at the omega end of the molecule, are desirable for industrial applications, but are produced by only a few natural systems and at levels that are too low for practical replacement of petroleum-based sources of monome...Fri, 29 Apr 2016 12:41:52 GMTlicensing@iastate.edu of linseed oil-derived materials as rejuvenators of vacuum tower bottom and reclaimed asphalt pavement Iowa State University researchers have developed formulations to use bio-derived materials as flux and/or rejuvenators for using vacuum tower bottoms (VTB) and reclaimed asphalt pavement (RAP) in warm mix asphalt. Description: Heated bodied linseed oil and partially hydrogenated heated bodied linseed oil were used as flux and/or rejuvenators for asphalt binders made from vacuum tower bottoms (VTB). These bio-derived materials were able to improve the binder performance grade from 76-10 to PG 70-22 and PG 64-22 grades. As VTB is at a distinct price advantage over other binder material...Thu, 28 Apr 2016 14:15:59 GMTlicensing@iastate.edu lens device for tunable harmonic generation of laser beams in KKBBF/RBBF crystals ISU researchers have developed an improvement to KBBF crystal systems for the generation of ultraviolet laser light by creating an alternative prism geometry that eliminates the need for contacting fluid or optical coupling devices. Description: Lasers consisting of light from the ultra-violet portion of the spectrum have both scientific and commercial applications. Scientifically, vacuum ultraviolet (VUV) lasers can be used in angle resolved photoemission spectroscopy to study the electronic parameters of solids. Commercially VUV lasers are of interest in semiconductor manufacturing...Thu, 28 Apr 2016 14:15:58 GMTlicensing@iastate.edu Protein and Biochar Fertilizer ISU researchers have developed a new, bio-char-based fertilizer that solves the problem of biochar application and incorporated additional biorenewable components for soil conditioning and enhanced nutrient availability. Description: Consumer demands for environmentally friendly products continue to rise. Public concern over pollution and other negative environmental impacts from chemical production have created a great interest in alternative chemical products produced from bio-based feedstocks and end-use chemical products that incorporate both bio-based chemicals and green chemist...Thu, 07 Apr 2016 13:57:07 GMTlicensing@iastate.edu (Gamma)-Ni+(Gamma Prime)-Ni3Al-Based Compositions for High-Temperature, Degradation-Resistant Structural Alloys, 07 Apr 2016 13:42:59 GMTlicensing@iastate.edu Device for Generation of Broadband Terahertz Radiation Iowa State University and Ames Laboratory researchers have developed a metamaterials-based terahertz emitter that could drastically improve communication speeds and imaging resolution. Description: The terahertz gap, which lies between the infrared and millimeter spectral regions (from approximately 100 GHz to 15THz) poses one of the most demanding challenges for technology and fundamental science today. The lack of efficient light sources and detectors makes THz physics one of the least explored parts of the entire electromagnetic spectrum. This is despite the underlying demand in t...Mon, 22 Feb 2016 12:25:02 GMTlicensing@iastate.edu Carbon Nanospheres for the Continuous Production/Extraction of High Value Fatty Acids from Algae The technology involves the use of specialized mesoporous carbon nanospheres (MCN) for the selective extraction of high value fatty acids produced by algae in culture. The process allows for the removal of the oil form the algae and the selective sequestration of the oils in the MCN and does not cause terminally detrimental effects to the algal cells therefore allowing the process to be continuous. Current methods for extraction involve drying, grinding and resuspension of the biomass which results in the destruction of the algal cells. The new technology allows for the selective ...Wed, 03 Feb 2016 10:53:00 GMTlicensing@iastate.edu<![CDATA[Foxtail Mosaic Virus Transient Gene Silencing Vector for Maize & other Monocots]]> Plant viruses have been widely used as vectors for foreign gene expression and virus-induced gene silencing (VIGS). A limited number of viruses have been developed into viral vectors for the purpose of VIGS in monocotyledonous plants and only one has been shown to infect maize. ISU researchers have developed a new DNA-based VIGS system derived from Foxtail mosaic virus (FMV) which is able to establish systemic infection and silencing of endogenous maize genes homologous to gene fragments inserted into the FMV viral vector. Proof-of-concept VIGS applications of this vector system was a...Mon, 01 Feb 2016 12:20:34 GMTlicensing@iastate.edu of room temperature cold-plastic forming or patterning of amorphous alloys, 17 Dec 2015 10:26:09 GMTlicensing@iastate.edu as a Tool to Control Cyst Nematodes, 08 Dec 2015 14:16:57 GMTlicensing@iastate.edu S1 Protein ELISA for Detection of Porcine Delta Coronavirus Researchers at Iowa State University have developed an ELISA assay for the detection of Porcine Delta Coronavirus based on the use of a recombinant S1 viral protein. Description: Porcine Delta Coronavirus (PDCoV) was first diagnosed in North America in early 2014 where it was associated with enteric disease in pigs. While assays detecting nucleic acids of the virus were implemented quickly, assays to detect anti-PDCoV antibodies lagged far behind. Iowa State Researchers led the development of an indirect PDCoV anti-IgG enzyme-linked immunosorbent assay (ELISA) based on the putative S...Tue, 08 Dec 2015 13:18:28 GMTlicensing@iastate.edu S1 Protein ELISA for Detection of Porcine Epidemic Diarrhea Virus Researchers at Iowa State University have developed an ELISA assay for the detection of Porcine Epidemic Diarrhea Virus (PEDV) based on the use of the PEDV S1 protein. The assay is capable of detecting anti-PEDV antibody of various classes (IgG, IgA or IgM) in serum, oral fluid, feces, and in colostrum and milk. Description: Laboratory diagnosis for PEDV is often performed using PCR as PEDV is difficult to culture; in addition, PEDV can resemble transmissible gastroenteritis (TGE) clinically, so it is important for herd management to understand the cause of acute diarrhea in infected...Tue, 08 Dec 2015 13:18:27 GMTlicensing@iastate.edu Deltacoronavirus, 08 Dec 2015 13:18:26 GMTlicensing@iastate.edu Improved Synthsis of Coumalic Acid and Malic Acid from a Common Intermediate, 08 Dec 2015 12:58:27 GMTlicensing@iastate.edu general efficient Gutzwiller solver for electronic structure simulation package, 08 Dec 2015 08:45:19 GMTlicensing@iastate.edu Forward Automatic Insulin Delivery System Researchers at Iowa State University have developed a feedforward control system for Type 1 Diabetes management. Feedforward control systems, while requiring a more exhaustive model to be properly implemented, can provide better control than typical feedback systems. Moreover, the technology involves non-invasive techniques to manage insulin levels in the body, in contrast to feedback control systems which would require continuous monitoring of blood glucose concentration. Description: The technology aims to develop a feedforward control mechanism for Type 1 Diabetes treatment that u...Tue, 08 Dec 2015 08:45:18 GMTlicensing@iastate.edu Novel Facultative Methylotroph, Methylocystis daltona SB2, 08 Dec 2015 08:45:17 GMTlicensing@iastate.edu Light Absorbing Photoremovable Protecting Groups, 08 Dec 2015 08:45:14 GMTlicensing@iastate.edu Nonhost Resistance Genes(s) for Engineering Soybeans Resistant to Sudden Death Syndrome, 08 Dec 2015 08:05:08 GMTlicensing@iastate.edu Genes for Enhanced Sudden Death Syndrome Resistance Endogenous soybean genes with potential to yield soybean varieties with improved resistance to sudden death syndrome (SDS) in soybeans. Description: ISU researchers have identified ten soybean genes with markedly reduced gene expression following infection by the fungus Fusarium virguliforme that causes sudden death syndrome in soybeans. The genes are being characterized for resistance to sudden death syndrome in transgenic soybeans and some of the genes look promising. If effective these findings may lead to the development of commercially important sudden death syndrome resistant s...Tue, 08 Dec 2015 07:58:25 GMTlicensing@iastate.edu Advance Reservation with Delayed Allocation Over Wavelength-Routed Networks, 07 Dec 2015 15:11:52 GMTlicensing@iastate.edu and Apparatus for Computing Time Decayed Aggregates over Asynchronous Streams, 07 Dec 2015 15:02:35 GMTlicensing@iastate.edu Temperature Upgrading and Stabilization of Lignin-derived Phenolic Oligomers in Bio-Oil Iowa State University researchers have developed a process for upgrading of reactive bio-oil without excess char production or fouling of catalysts. Description: Bio-oils from pyrolysis operations are complex mixtures of reactive chemicals, and resist techniques conventionally used in the petrochemical refining industry to upgrade crude oil products. The high reactivity of the bio-oil is due to an abundance of unsaturated carbon-carbon bonds as well as a prevalence of carbonyl groups. These tend to react with one another when exposed to high temperatures and active catalysts, resulti...Mon, 07 Dec 2015 14:53:34 GMTlicensing@iastate.edu Antibodies against a Novel Isoform of Human Protein Kinase C Delta, 07 Dec 2015 14:49:15 GMTlicensing@iastate.edu suis Isolates, 07 Dec 2015 14:44:02 GMTlicensing@iastate.edu Basis and Test for Severe Combined Immune Deficiency in Pigs, 07 Dec 2015 14:39:38 GMTlicensing@iastate.edu Strains of Mycoplasma bovis, 07 Dec 2015 14:39:38 GMTlicensing@iastate.edu of extracted lignin in a continuous reactor, 07 Dec 2015 14:24:51 GMTlicensing@iastate.edu by Mitochondria-targeted Metformin, 07 Dec 2015 14:13:58 GMTlicensing@iastate.edu from oligomeric polyesters of isosorbide, 07 Dec 2015 13:58:23 GMTlicensing@iastate.edu Influenza Viruses for Vaccine and Diagnostics, 07 Dec 2015 13:27:44 GMTlicensing@iastate.edu Large Scale Plant Phenotyping Instrumentation Iowa State University researchers have developed a microfluidic device to screen genotype-to-phenotype interactions.Description: Through an array of miniature greenhouses (MGHs), vertical microfluidic seed chips (MSCs), and microfluidic control logic. The plant growth system can provide maximal environmental flexibility in large- and multi-scale study of plant-environment interactions. Each MGH can flexibly regulate relative humidity (RH), C02 level, and light intensity via controlled microfluidic capillary filling, controlled chemical reaction, and liquid crystal technologies, respec...Mon, 07 Dec 2015 13:16:16 GMTlicensing@iastate.edu Shape Measurement with Binary Dithered Patterns, 07 Dec 2015 12:42:12 GMTlicensing@iastate.edu Temperature Ferromagnetic Gd5Si4 MRI Contrast Agent Summary: Iowa State University and Ames Laboratory researchers have developed a method to create gadolinium silicide nanoparticles which retain ferromagnetic properties at room temperature. Description: This innovative method creates Gd5Si4 nanoparticles that retain the ferromagnetic properties of the bulk material at room temperature. These nanoparticles may be useful as a MRI contrast agent or for other applications that would benefit from materials that highly respond to a magnetic field, such as transcranial magnetic stimulation, MRI thermometry, and hyperthermic cancer treatment. The g...Mon, 07 Dec 2015 11:38:09 GMTlicensing@iastate.edu Actuator and Methods of Droplet Manipulation, 07 Dec 2015 11:38:08 GMTlicensing@iastate.edu Senecavirus A as Etiology of Vesicular Disease and Methods to Propagate the Virus in Vitro Iowa State University researchers have identified, purified, and characterized cell culture-derived isolates of Senecavirus. A. The full genome sequence of the new isolates revealed that the isolates are genetically distinct from previously known Senecavirus A viruses. Description: Genetic changes/mutations have made the virus virulent, thus accounting for the 2015 vesicular disease outbreak in show and commercial pigs which have been seen in a number of States in the Midwest including IA, SD, IL, IN, MO, MN. From the rapid spreading and frequent identification of the virus, research...Mon, 07 Dec 2015 11:10:38 GMTlicensing@iastate.edu Senecavirus A as Etiology of Vesicular Disease and Methods to Propagate the Virus in Vitro Iowa State University researchers have identified, purified, and characterized cell culture-derived isolates of Senecavirus. A. The full genome sequence of the new isolates revealed that the isolates are genetically distinct from previously known Senecavirus A viruses. Description: Genetic changes/mutations have made the virus virulent, thus accounting for the 2015 vesicular disease outbreak in show and commercial pigs which have been seen in a number of States in the Midwest including IA, SD, IL, IN, MO, MN. From the rapid spreading and frequent identification of the virus, research...Mon, 07 Dec 2015 11:10:37 GMTlicensing@iastate.edu electronics with improved electrical conductivity by incorporating insoluble metals, 07 Dec 2015 10:17:51 GMTlicensing@iastate.edu Tentacle Actuator ISU researchers have invented a soft material-based manipulator for delicate, fragile microscale objects. It is based on a thin-walled elastomeric microtube with an asymmetric wall thickness distribution and one end closed. Upon applying air pressure from the open end, the microtube becomes elongated non-uniformly, bending towards the thick-walled side. This type of bending, however, is often insufficient to induce a spiraling which mimics the coiling motion of biological tentacles, such as those of the octopus. To amplify the bending into multi-turn spiraling, we installed a smal...Mon, 07 Dec 2015 10:17:50 GMTlicensing@iastate.edu Halo Transcranial Magnetic Stimulation Coil, 07 Dec 2015 10:17:50 GMTlicensing@iastate.edu Continuous - Flow Winery Iowa State University researchers have developed a miniature continuous-flow winery with immobilized yeast cells, mass transport via porous membranes, in-line alcohol sensing and temperature control. Description: Today, wine is typically produced in large batches, with volumes 10-100,000 liters. Alcoholic fermentation occurs within 2 weeks, and the remaining winemaking operations occur within weeks to months. Yeast cells are dispersed in the juice. Monitoring of fermentation and production is done by sampling. This invention uses a continuous flow rather than a batch approach. Volum...Mon, 07 Dec 2015 10:17:49 GMTlicensing@iastate.edu Barrier Vaccine Device, 07 Dec 2015 10:17:48 GMTlicensing@iastate.edu rare earth metals using bismuth extractant, 07 Dec 2015 09:57:19 GMTlicensing@iastate.edu of dysprosium-enriched iron alloy from magnet scrap alloy via selective separation of rare earth elements, 07 Dec 2015 09:50:52 GMTlicensing@iastate.edu of the Nodulating, Nitrogen-Fixing Soybean Symbiont Bradyrhizobium japonicum to Increase Plant Disease Resistance, 07 Dec 2015 09:42:34 GMTlicensing@iastate.edu Separation of Terbium Oxide, 24 Nov 2015 14:07:03 GMTlicensing@iastate.edu Chemical Separation of Rare-Earth Oxalates, 24 Nov 2015 14:07:02 GMTlicensing@iastate.edu Loop 3D Printing, 03 Nov 2015 12:48:55 GMTlicensing@iastate.edu Phase Synthesis of Highly Processible Nanocrystalline LiZnP and Similar Ternary Semiconductors, 03 Nov 2015 12:48:54 GMTlicensing@iastate.edu Nitrate System for Precision Management of Nitrogen Fertilizer Applications The soil nitrate sensing system allows nitrate to be analyzed rapidly in-real-time in the field. By measuring nitrate at multiple locations along with GPS coordinates for each location, the system can be used to rapidly generate a map of soil nitrate concentrations, which can be used as the basis for precision nitrogen fertilizer applications. Alternatively the sensor can be attached to (integrated with) a fertilizer applicator, allowing real time modulation of nitrogen fertilizer application rates based on measured soil nitrate levels. The soil nitrate sensing technology will mak...Tue, 03 Nov 2015 12:48:53 GMTlicensing@iastate.edu Mechanical Nanopolishing and Motor Oil for Self-Healing Metals and Ceramics Iowa State University and Ames Laboratory researchers have developed a process to produce extremely flat and smooth surfaces on hard materials without involving a chemical etchant. Description: Chemical mechanical polishing (CMP) is a process used to create defect-free, smooth and flat surfaces, primarily for the semiconductor industry, and involves both mechanical polishing and chemical etching. CMP slurries (which provide the physical interface between the sample and the polishing equipment) typically consist of an abrasive (most often a metal oxide such as silica, ceria, alumina o...Tue, 03 Nov 2015 12:48:52 GMTlicensing@iastate.edu Isomerization of Muconic Acid, 03 Nov 2015 11:49:41 GMTlicensing@iastate.edu Nylon: Polycondensation of 3-Hexenedioic Acid with Hexamethylenediamine, 03 Nov 2015 11:49:39 GMTlicensing@iastate.edu Hydrogenation of Muconic Acid for the Production of Biorenewable Synthetic Polymer Precursors, 03 Nov 2015 11:49:38 GMTlicensing@iastate.edu Plasma Throttled Combustion of Energetic Materials Future mission requirements of energetic material systems demand the ability to a tune the output (burning rate, thrust, specific impulse, radiant emission) of a broad range of energetic materials. More specifically for solid propellants, considerable work has been conducted on the development of electrical and valved throttling techniques. However, these techniques are either formulation-specific or are propellant temperature limited. Conversely, the proposed plasma throttling technique has been demonstrated with a number of solid propellant and pyrotechnic compositions and is not fo...Tue, 22 Sep 2015 08:10:19 GMTlicensing@iastate.edu Inducing Genotype for Field and Specialty Corn, 07 Aug 2015 07:09:34 GMTlicensing@iastate.edu Regulating Ear Productivity Traits in Maize, 07 Aug 2015 06:46:51 GMTlicensing@iastate.edu Monoclonal Anti Clostridium Perfringens Type D epsilon Toxin Antibody (Clone# 4D6) The 4D6 monoclonal antibody can detect nanogram quantities by Western blotting of both the Clostridium perfringens epsilon proto-toxin as well as the activated toxin Description: The epsilon toxin is one of 12 protein toxins produced by Clostridium perfringens, a Gram positive, anaerobic spore-forming rod. There are five strains of C. perfringens, designated A through E. Each strain produces a unique spectrum of toxins. The epsilon toxin is made by types B and D. This toxin is a pore-forming protein; it causes potassium and fluid leakage from cells. In addition to the epsilon toxin, ...Mon, 20 Jul 2015 14:29:28 GMTlicensing@iastate.edu Sequence Models, 11 Jun 2015 13:19:45 GMTlicensing@iastate.edu Room-temperature Polymerization of Bio-based Multiaziridine-containing Compounds, 11 Jun 2015 07:46:06 GMTlicensing@iastate.edu synthesis of alkali metal hydrides at room temperature, 11 Jun 2015 07:46:05 GMTlicensing@iastate.edu Vibration Energy Harvester, 01 Jun 2015 12:02:35 GMTlicensing@iastate.edu of Automated Test Generation for Simulink/Stateflow to Reachability and its Novel Resolution, 01 Jun 2015 12:02:34 GMTlicensing@iastate.edu of Wettability Properties of Copper for Heat Transfer Applications Summary: Iowa State University researchers have demonstrated enhanced heat transfer efficiency for phase change operations. Description: Iowa State University researchers have produced biphilic copper surfaces by chemical modification of the surface. Using this method, spatially controlled hydrophilic and hydrophobic areas exist proximately on a single surface; the hydrophilic areas promote contact between the liquid phase and the heat transfer surface, leading to an enhancement in the critical heat flux, while the hydrophobic areas increase nucleation sites, resulting in an enhan...Mon, 01 Jun 2015 12:02:33 GMTlicensing@iastate.edu Buckypaper Fabrication through Shear Alignment, 01 Jun 2015 12:02:33 GMTlicensing@iastate.edu Bee Feeding Inhibitor, 01 Jun 2015 12:02:32 GMTlicensing@iastate.edu of Flexible Capacitive Strain Gauges in Tires, 01 Jun 2015 12:02:31 GMTlicensing@iastate.edu Catalysts for Isomerization of Glucose to Fructose, 01 Jun 2015 11:49:51 GMTlicensing@iastate.edu of Low-Cost Carbon Catalyst Materials, 01 Jun 2015 11:49:51 GMTlicensing@iastate.edu for In-Situ, Wireless Soil Sensing, 01 Jun 2015 11:49:50 GMTlicensing@iastate.edu Silver Alloy Films with Controlled Architectures, 01 Jun 2015 11:49:49 GMTlicensing@iastate.edu Mechanochemical Synthesis of Alane (AlH3) at Room Temperature Summary: Iowa State University and Ames Laboratory researchers have developed a process for the synthesis of alane with quantitative yields at ambient temperature and moderate hydrogen or ambient gas pressure while controlling side reactions Description: Alane exceeds the DOE performance criteria for hydrogen storage for transportation vehicles, but does not have a cost-efficient production route. Synthesis of alane by metathesis reactions in organic solvents is inefficient because of the need to remove solvents from the resultant alane solvates that inevitably leads to thermal decompositi...Mon, 01 Jun 2015 11:49:48 GMTlicensing@iastate.edu of reactive gas atomized titanium aluminide powder, 01 Jun 2015 11:49:48 GMTlicensing@iastate.edu Wave Axial Nanometry (SWAN) for Superresolution Microscopy Summary: Iowa State University researchers have an approach for performing 3-D measurements of single molecules with nanometer accuracy and precision. Description: Despite its importance as a research tool for understanding cellular functions, the optical resolution of light microscopy has imposed limitations on observing and measuring cellular components and structures. The advent of superresolution microscopy techniques, which enable imaging of nanostructures and processes at X-Y resolutions of approximately 20 nm, opens new opportunities for exploring cell biology and has many other appl...Mon, 01 Jun 2015 11:48:18 GMTlicensing@iastate.edu Management with Metamaterials, 01 Jun 2015 11:48:18 GMTlicensing@iastate.edu Biopolymers for Use as Carbon Fiber Precursors, 01 Jun 2015 11:48:17 GMTlicensing@iastate.edu Stability of Gas Atomized Reactive Powders Through Multiple Step In-Situ Passivation, 01 Jun 2015 11:48:16 GMTlicensing@iastate.edu Method for Wide Field-View Imaging, 01 Jun 2015 11:36:17 GMTlicensing@iastate.edu Cell Lines for Mycoplasma bovis Two mouse/mouse stable hybridomas (87, 163) have been developed against M. bovis strain M23. M. bovis is associated with a variety of bovine diseases including arthritis and pneumonia of calves and young cattle, mastitis, and genital tract infections. It is considered the most virulent bovine mycoplasma in the US. Ascite fluid from these two hybridoma cells can be use in formalin-fixed, paraffin-embedded tissues and is highly specific in ELISA, IFA, and immunoblot analyses to six strains of M. bovis (M23, Emm, Bat, 1315, M66, and M84) originating from cases of bovine pneumonia or ...Fri, 22 May 2015 14:32:59 GMTlicensing@iastate.edu Mosaic Virus as a Transient Expression Vector for Soybeans Identifying potentially useful genes for improving soybean can be time consuming. ISU researchers have developed a rapid method for expressing genes in soybean using soybean mosaic virus. These unpatented materials are being made available for non-exclusive license to interested third parties. Description: Researchers at Iowa State University have developed a virus-based transient expression vector for soybeans. This technology will allow rapid testing of the effect of genes of interest, without having to wait months for transformation of soybean plants with the target genes. The vir...Fri, 22 May 2015 14:32:58 GMTlicensing@iastate.edu"September Sun" Seaside Alder Cultivar (Alnus maritima), 22 May 2015 14:32:56 GMTlicensing@iastate.edu Cell Lines for the Production of Monoclonal Antibodies Against Mycoplasma Hyopneumonia cell lines F1B6 and F2G5 produce monoclonal antibodies which are unique in their ability to inhibit the in vitro adherence of M. hyopneumoniae to swine cilia. The tracheal cilia are the natural targets to which the mycoplasma binds during in vivo infection. The antibodies are important in the characterization of M. hyopneumoniae isolates by immunoblotting and adherence inhibition, and in purification of M. hyopneumoniae adhesins Application: - Veterinary diagnostics- Vaccine quality controlThe cell lines are available for non-exclusive licensing. Intellectual Property:T...Fri, 22 May 2015 13:25:36 GMTlicensing@iastate.edu Tap Tester (CATT) for Inspection of Composite and Metal Honeycomb Structures This technology is an instrumented tap test system that provides quantitative, image-based data regarding the mechanical properties of an inspection area. Driven by a laptop PC, the system produces two dimensional images (or "C-scans") that reveal flaws, damages, repairs and substructures in complex bonded structures such as metal honeycomb sandwiches and composite structures. It produces images of the local stiffness of the component, and the stiffness derived from the tap test was shown to agree with that obtained by static load tests. The instrument generates images that reveal...Tue, 19 May 2015 12:04:53 GMTlicensing@iastate.edu Anaerobic Reactor for Municipal and Industrial Waste Processing, 19 May 2015 12:04:46 GMTlicensing@iastate.edu Controlled Ferroelectric Barium Titanate (BaTiO3) Nanocrystals Summary: Iowa State University researchers have developed a method for producing nanoscale ferroelectric modules for the fabrication of electronic devices. Description: Perovskite-type mixed metal oxide materials with general formula of ABO3, of which barium titanate (BaTiO3) is the most studied, have received tremendous research attention in the past decades due to their unique ferroelectric, catalytic, sensing, superconducting, and optical properties for use in thin-film capacitors, pyroelectric detectors, electrooptic modulators, transducers, actuators, optical memories, and nonlinear o...Thu, 14 May 2015 14:53:31 GMTlicensing@iastate.edu Preparation of Nanoparticles for Biomedical and Chemical Applications, 14 May 2015 14:53:30 GMTlicensing@iastate.edu Method for Conversion of Cellulose to High-Value Materials, 14 May 2015 14:53:28 GMTlicensing@iastate.edu Sensitive Foldable Oligomers, 14 May 2015 14:53:28 GMTlicensing@iastate.edu Production Method for Alloys Used in Harsh Environments, 14 May 2015 14:53:27 GMTlicensing@iastate.edu Production of Gold Nanoparticles, 14 May 2015 14:53:26 GMTlicensing@iastate.edu Synthesis of A-Type Procyanidins, 14 May 2015 14:53:24 GMTlicensing@iastate.edu of Producing Alpha-Olefins from Fatty Acids Iowa State University researchers have developed an industrially optimized reaction for the transformation of fatty acids into bio-based alpha olefins for the production of specialty chemicals. Description: The versatility of alpha-olefins makes these compounds useful for many specialty chemicals, as well as for production of surfactants and lubricants. Reducing the dependence on petroleum-based feedstock for the preparation of alpha-olefins has been the focus of research into utilizing renewable sources for bio-based production of alpha-olefins. As part of this research effort, Iowa...Thu, 14 May 2015 14:53:20 GMTlicensing@iastate.edu to Efficiently and Economically Obtain Microorganisms and Microalgae, 14 May 2015 14:53:17 GMTlicensing@iastate.edu Resistivity Contact to Iron-Pnictide Superconductors Description: Superconductors are materials which carry electrical current without dissipation. However, feeding electrical current into a superconductor generates heat dissipation in the contacts and degrades maximum attainable current value. The degradation in contacts is also different depending on the different chemical nature of the superconducting materials. Iron-pnictide based superconductors have a number of superior properties as compared to other known high temperature superconductors, and due to their high critical magnetic fields, can be competitive alternatives for generating hig...Thu, 14 May 2015 14:53:16 GMTlicensing@iastate.edu for Fabrication of Efficient Solar Cells, 14 May 2015 14:53:15 GMTlicensing@iastate.edu Sulfide Removal Technology for Wastewater Treatment Iowa State University researchers have developed a method for removing sulfide compounds from wastewater and reducing their concentrations to as low as 1 ppmv without disturbing methanogenesis. Description: Sulfur compounds present in industrial wastewater have the potential to be converted into highly corrosive and malodorous hydrogen sulfide, which not only can be detrimental to the performance of metal catalysts employed in thermo-catalytic processes, but also reduces the quality of methane obtained as a renewable energy source from wastewater treatment in bioreactors. Current app...Thu, 14 May 2015 14:53:14 GMTlicensing@iastate.edu Efficient DNA-Based Viral Gene Silencing Vector System for Soybean Functional Genomics, 13 May 2015 11:03:21 GMTlicensing@iastate.edu An Optimal Oligonucleotide Design and Analysis Tool, 13 May 2015 11:03:20 GMTlicensing@iastate.edu II for Engineering Soybean for Disease Resistance Root and stem rot of soybeans causes an estimated $300 million annually in economic losses to the agriculture industry. ISU researchers have identified a gene in that may be able to be used to create broad-spectrum resistance to root and stem rot, as well as other diseases, in soybeans. Description: Root and stem rot of soybeans is caused by the oomycete pathogen Phytophthora sojae and results in significant economic losses each year in the agriculture industry. In the past, growing Phytophthora-resistant cultivars has been the major method of controlling this disease. Recently, howe...Wed, 13 May 2015 11:03:19 GMTlicensing@iastate.edu Dose Controlled Release Vaccine Formulations Using Polyanhydride Microspheres, 13 May 2015 11:03:15 GMTlicensing@iastate.edu Transformation and Regeneration Using Half-Seed Explants, 13 May 2015 11:03:14 GMTlicensing@iastate.edu Drug Delivery Platform for Targeting Intracellular Pathogens, 13 May 2015 11:03:10 GMTlicensing@iastate.edu Controlling Plant Growth, 13 May 2015 11:03:09 GMTlicensing@iastate.edu Plant Growth through Mobile RNA Signals Summary: Iowa State University researchers have identified mobile RNAs in potatoes whose overexpression enhances plant growth. Description: Plants have evolved intricate signaling pathways to regulate growth and other physiological processes. Light quality and duration play an important role in providing external cues perceived by the plant. Photoperiod is an example of one such external signal that controls important physiological processes like flowering, dormancy, germination, senescence, and tuber formation. During tuber formation, a graft-transmissible signal initiated in the leaves mo...Wed, 13 May 2015 11:03:08 GMTlicensing@iastate.edu and Fingerprinting Digital Communication Devices for Improved Security Summary: Researchers at Iowa State University have developed a method for monitoring the communication signature of digital communication devices that can be used for authentication and other security applications. Description: The proliferation of digital communications devices and wireless access points has lead to increasing security concerns; these security concerns generally fall under the areas of digital forensics, intrusion detection, and authentication. However, strategies for mitigating these concerns are often inadequate or create a significant administrative overhead burden, su...Fri, 08 May 2015 15:44:36 GMTlicensing@iastate.edu Sensitive Real-Time Data-Driven Music Algorithms, 08 May 2015 15:44:35 GMTlicensing@iastate.edu Spatial Multiplexing for Wireless Applications Summary: ISU researchers have developed a cooperative spatial multiplexing strategy that requires only a single antenna Description: Wireless communication environments are increasingly resource-constrained, with a limited and highly regulated spectrum. In addition, the practicality of the wireless terminal is constrained by a finite energy supply and space limitations. To address these problems, ISU researchers have developed a cooperative spatial multiplexing strategy that requires only a single antenna by creating a virtual antenna array from a collection of antennas belonging to other ...Fri, 08 May 2015 15:41:57 GMTlicensing@iastate.edu Geared, Continuously Variable Speed Transmission Most vehicles today use transmissions that provide three or four specific speed ratios, but do not necessarily allow the car engine to operate at optimum speed. To increase the efficiency of vehicle operation, ISU researchers have developed a continuously variable speed transmission that can improve performance. Description: Most cars on the road today use transmissions that supply three or four specific speed ratios, but do not automatically optimize vehicle operation. Some vehicles today use variable speed belt drives or toroidal, continuously variable speed transmissions. However,...Fri, 08 May 2015 15:38:33 GMTlicensing@iastate.edu Timing Error Detection and Recovery to Dynamically Improve Superscalar Processor Performance: SPRIT3E ISU researchers have developed a method that enables modern high performance computer processors to operate reliably at speeds higher than previously possible.Description: Modern processors (and in fact all synchronous logic circuits) use a clock to control execution of the circuit. The speed of this clock, which in large part determines how quickly the processor runs applications, is traditionally limited by worst case delay. The resulting propagation delay is difficult to determine precisely for three main reasons. First, variations induced when computer chips are produced create va...Fri, 08 May 2015 15:35:21 GMTlicensing@iastate.edu Active Noise Control System, 08 May 2015 15:20:44 GMTlicensing@iastate.edu Method for Machining Metallic Foam, 08 May 2015 15:20:43 GMTlicensing@iastate.edu Rotavirus Isolates for Improved Vaccines: Group A, 08 May 2015 09:01:43 GMTlicensing@iastate.edu Rotavirus Isolates for Improved Vaccines: Group C, 08 May 2015 09:01:43 GMTlicensing@iastate.edu Recycling for More Efficient Data Transmission, 07 May 2015 14:16:30 GMTlicensing@iastate.edu Depth-Optimal Mapping of Logic Chains in Reconfigurable Fabrics, 07 May 2015 10:01:12 GMTlicensing@iastate.edu Element Architecture for Improving Logic Chain Operations in Programmable Devices, 07 May 2015 10:01:12 GMTlicensing@iastate.edu with Footprints: A Novel Technique for Location Privacy Protection in Location-Based Services, 07 May 2015 10:01:11 GMTlicensing@iastate.edu REconfigurable Block Encryption Logic for Cyber Security, 07 May 2015 10:01:11 GMTlicensing@iastate.edu Film-Cooling Shaped Holes, 07 May 2015 10:01:10 GMTlicensing@iastate.edu Noise Control System for Use in Noise Cancelling Devices, 07 May 2015 10:01:09 GMTlicensing@iastate.edu Hot Gas Ingestion by Film-Cooling Jets via Flow-Aligned Blockers, 07 May 2015 10:01:08 GMTlicensing@iastate.edu Boron Material for Neutron Detection, 07 May 2015 10:01:07 GMTlicensing@iastate.edu Approach for Simulink/Stateflow Diagrams to Ease Analysis of Embedded Software, 07 May 2015 10:01:04 GMTlicensing@iastate.edu Interferometric Switch Utilizing Faraday Rotation, 07 May 2015 10:01:02 GMTlicensing@iastate.edu Polarized Thermal Emitter for More Efficient Thermophotovoltaic Devices, 07 May 2015 10:01:02 GMTlicensing@iastate.edu Photonic Software, 07 May 2015 10:01:01 GMTlicensing@iastate.edu to Determine Susceptibility to Root Lodging, 05 May 2015 11:02:48 GMTlicensing@iastate.edu Polymer Solar Cells, 05 May 2015 10:39:11 GMTlicensing@iastate.edu Eddy Current Coil Design for Nondestructive Evaluation, 05 May 2015 10:39:10 GMTlicensing@iastate.edu Switching Power Converter, 05 May 2015 10:39:08 GMTlicensing@iastate.edu Phased Array Antenna, 05 May 2015 10:39:07 GMTlicensing@iastate.edu Catalytic Core: A Novel Approach for Spinal Muscular Atrophy Treatment, 05 May 2015 10:39:06 GMTlicensing@iastate.edu of Polylactic Acid, 05 May 2015 10:39:02 GMTlicensing@iastate.edu Oxidation of Organic Substrates to Partially Oxidized Products, 05 May 2015 10:39:01 GMTlicensing@iastate.edu Spinning Process of Lignin for Fiber Production The technology enables an economical production of carbon fibers from biorenewable feedstock based on lignin, an abundant byproduct of paper manufacturing and cellulosic derived fuel. Description: Due to its complex interconnected structure, lignin is a very brittle biopolymer that cannot be spun, stretched or aligned, and spooled into fibers without modification. However, the potential use of lignin fibers as an economical, biorenewable carbon fiber precursor has made it an attractive compound for investigation. Iowa State University researchers have devised a method to improve the...Tue, 05 May 2015 10:39:00 GMTlicensing@iastate.edu Metal Photodeposition, 05 May 2015 10:38:59 GMTlicensing@iastate.edu for Selective Acid Transesterfication Iowa State University and Ames Laboratory are looking for industry partners to commercialize a newly developed bi-functional, heterogeneous catalyst that is designed to expel aqueous byproducts formed during transesterfications reactions. Description: The ability to separate functionalized mesoporous silica nanoparticles (MSNs) for recycling has enabled applications of these materials as heterogeneous catalysts in many chemical transformations. However, their sensitivity to hydrolysis and subsequent loss of catalytic performance has reduced the economic benefit potential of MSN catal...Tue, 05 May 2015 10:38:58 GMTlicensing@iastate.edu Pigs for Biomedical Research, 05 May 2015 10:38:58 GMTlicensing@iastate.edu Methods of Magneto-Optic Optical Switching, 04 May 2015 07:01:22 GMTlicensing@iastate.edu Synthesis Methods for N-acylethanolamines, 04 May 2015 07:01:21 GMTlicensing@iastate.edu Resistant Rice, 04 May 2015 07:01:20 GMTlicensing@iastate.edu Systems Design Suite (ASDS), 04 May 2015 07:01:19 GMTlicensing@iastate.edu Bovine Viral Diarrhea (BVD) Viruses for Improved Vaccines An Iowa State University researcher has purified a set of contemporary bovine viral diarrhea virus isolates that may be useful as vaccine strains. Description: The bovine viral diarrhea virus (BVDV) causes disease in cattle and other ruminants. Diseased animals may show respiratory and reproductive symptoms ranging from mild to very severe, in some cases resulting in the death of the animal. The disease primarily affects young cattle and usually results in mucosal lesions that can be misdiagnosed because of their similarity to infections by other viruses. BVDV effects significant ec...Mon, 04 May 2015 07:01:18 GMTlicensing@iastate.edu from Bio-Renewable Sources Summary: Polyurethane materials completely based on bio-renewable resources have been successfully developed at Iowa State University. Description: Polyurethanes are an important class of polymers with uses in a wide variety of materials. The raw materials for production of polyurethanes are polyols and diisocyantes, which are typically derived from petroleum-based feedstocks. While production of polyols from biorenewable sources such as vegetable oils has been successfully developed and implemented in commercially available products, production of diisocyantes from renewable sources has no...Mon, 04 May 2015 07:01:18 GMTlicensing@iastate.edu Assisted Catalyst for the One-Pot Sequestration and Conversion of Renewable Feedstocks into Fuels Iowa State University and Ames Laboratory researchers have developed a technology that provides a simplified and economical production of hydrocarbon fuel from renewable resources with higher energy potential compared to ethanol or biodiesel. The ability to achieve higher yields from lipid feedstock, and in particular algae oils, by not utilizing current methods of fatty acid conversion to methyl esters, makes this technology economically attractive. Iowa State University is looking for industry partners to commercialize this technology. Description: Conversion of fatty acids to biod...Mon, 04 May 2015 07:01:16 GMTlicensing@iastate.edu Adapted Haploid Inducer for Maize Iowa State University researchers have developed a new haploid inducer for maize that is adapted to growing conditions in the Midwest. Description: Inbred corn lines have two identical copies of their genome, and are valuable breeding resources since offspring are identical to their parent. Since offspring of hybrids are genetically segregating, hybrid seed needs to be generated from genetically stable, parental inbred lines. Development of traditional corn inbred lines starts from heterozygous plants and requires continued self-pollination, which takes five to eight generations befo...Mon, 04 May 2015 07:01:15 GMTlicensing@iastate.edu Strains of Western Corn Rootworm - Hopkinton Strain, 04 May 2015 07:01:14 GMTlicensing@iastate.edu and System for Manufacturing an Article Using Portable Hand-Held Tools, 04 May 2015 06:51:34 GMTlicensing@iastate.edu"Healthy Beef": Fatty Acid Synthase Genetic Markers Associated with a Healthier Fatty Acid Composition, 04 May 2015 06:51:32 GMTlicensing@iastate.edu and Cost Effective Preparation of Diverse Nanomaterials, 04 May 2015 06:51:31 GMTlicensing@iastate.edu for Simultaneous Single Molecule AFM and Fluorescence Measurements, 04 May 2015 06:51:31 GMTlicensing@iastate.edu Vibration Isolation Device Summary: Researchers have developed a low cost pneumatic isolation device (LCPID) that can be used in conjunction with a vibration isolation platform technology to help reduce whole-body vibrations and their health consequences that workers may be subjected to when driving or operating equipment, trucks, or other vehicles. Description: Whole-body vibration is a physical occupational hazard in many workplaces. Workers typically subjected to this type vibration are operators or drivers of numerous kinds of vehicles used in agriculture, construction, highway trucking, and utility industries. O...Sun, 03 May 2015 15:15:20 GMTlicensing@iastate.edu Shell Wind Turbine Tower Constructed of UHPC for Taller Turbines, 03 May 2015 15:15:19 GMTlicensing@iastate.edu Dispenser for Refrigerator with Bottom Mount Freezer, 03 May 2015 15:15:18 GMTlicensing@iastate.edu Benzobisoxazole Polymers for Organic Semiconductors, 03 May 2015 15:15:17 GMTlicensing@iastate.edu Isosorbide-Based Tackifiers, Adhesives, and Cross-Linked Resins, 03 May 2015 15:15:13 GMTlicensing@iastate.edu